CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF - SHANGHAI JEMINCARE PHARMACEUTICALS CO LTD

Title:

CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2020/074004

Kind Code:

A1

Abstract:

Provided are a compound of formula (I), an optical isomer thereof, a pharmaceutically acceptable salt thereof, uses of said compoung acting as a STING agonist.

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Inventors:

GUO SHUCHUN (CN)
PENG JIANBIAO (CN)
LIU YANG (CN)
GUO HAIBING (CN)

Application Number:

PCT/CN2019/110800

Publication Date:

April 16, 2020

Filing Date:

October 12, 2019

Export Citation:

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Assignee:

SHANGHAI JEMINCARE PHARMACEUTICALS CO LTD (CN)
JIANGXI JEMINCARE GROUP CO LTD (CN)

International Classes:

A61K31/7084; C07H19/213; A61P35/00

Domestic Patent References:

WO2017161349A1	2017-09-21
WO2018065360A1	2018-04-12
WO2019043634A2	2019-03-07
WO2017123657A1	2017-07-20

Foreign References:

CN102199183A	2011-09-28
CN201811188184A	2018-10-12
CN201811301854A	2018-11-02
CN201811367721A	2018-11-16
CN201910129734A	2019-02-21
CN201910463705A	2019-05-30

Other References:

YI ET AL.: "Single Nucleotide Polymorphisms of Human STING can affect innate immune response to cyclic di-nucleotides", PLOS ONE, vol. 8, no. 10, 2013, pages e77846, XP055315013, DOI: 10.1371/journal.pone.0077846
See also references of EP 3868773A4

Attorney, Agent or Firm:

SHANGHAI BESHINING LAW OFFICE (CN)

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