Title:
CYCLODEXTRIN-BASED METAL ORGANIC FRAMEWORK MATERIAL AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2020/215638
Kind Code:
A1
Abstract:
The present disclosure belongs to the field of chemical industry production, and particularly relates to a cyclodextrin-based metal organic framework material and a preparation method therefor. The preparation method comprises the following steps: (1) formulating a supersaturated γ-cyclodextrin alkaline alcohol aqueous solution containing alkali metal ions; (2) heating to obtain a hot γ-cyclodextrin solution; and (3) cooling the hot γ-cyclodextrin solution of step (2), and performing crystallization and separation to obtain a cyclodextrin-based metal organic framework material. The cyclodextrin-based metal organic framework material has perfect crystallization and large specific surface area, and crystallization and specific surface area properties of same are similar to those of materials prepared by means of traditional methods. The important thing is that the synthesis operation thereof is simple, green and environmentally friendly, and the time required is shortened from a few hours or even tens of hours to a few minutes, which significantly improves the synthesis efficiency and is conducive to industrial scale production.
Inventors:
LI XIAOXI (CN)
CHI CHENGDENG (CN)
CHEN LING (CN)
CHI CHENGDENG (CN)
CHEN LING (CN)
Application Number:
PCT/CN2019/113455
Publication Date:
October 29, 2020
Filing Date:
October 25, 2019
Export Citation:
Assignee:
UNIV SOUTH CHINA TECH (CN)
International Classes:
C08G83/00
Foreign References:
| CN105814118A | 2016-07-27 | |||
| CN110054782A | 2019-07-26 |
Other References:
LI, HAIYAN ET AL.: "Composite CD -MOF Nanocrystals-Containing Microspheres for Sustained Drug Delivery", THE ROYAL SOCIETY OF CHEMISTRY, vol. 9, 13 April 2017 (2017-04-13), pages 7454 - 7463, XP055746114, DOI: 10.1039/C6NR07593B
LIU, BOTAO ET AL.: "Microwave-Assisted Rapid Synthesis of y-Cyclodextrin Metal-Organic Frameworks for Size Control and Efficient Drug Loading", CRYSTAL GROWTH & DESIGN, vol. 17, 20 February 2017 (2017-02-20), pages 1654 - 1660, XP055624796, DOI: 10.1021/acs.cgd.6b01658
SMALDONE, RONALD A. ET AL.: "Metal-Organic Frameworks from Edible Natural Products", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 49, 16 August 2010 (2010-08-16), pages 8630 - 8634, XP055214613, DOI: 10.1002/anie.201002343
LIU, BOTAO ET AL.: "Microwave-Assisted Rapid Synthesis of y-Cyclodextrin Metal-Organic Frameworks for Size Control and Efficient Drug Loading", CRYSTAL GROWTH & DESIGN, vol. 17, 20 February 2017 (2017-02-20), pages 1654 - 1660, XP055624796, DOI: 10.1021/acs.cgd.6b01658
SMALDONE, RONALD A. ET AL.: "Metal-Organic Frameworks from Edible Natural Products", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 49, 16 August 2010 (2010-08-16), pages 8630 - 8634, XP055214613, DOI: 10.1002/anie.201002343
Attorney, Agent or Firm:
GUANGZHOU HUAXUE INTELLECTUAL PROPERTY AGENCY CO., LTD. (CN)
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