Title:
DETECTION OF MALIGNANT TUMOR CELLS ANTIBODIES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/143507
Kind Code:
A1
Abstract:
Provided are anti-ROR2 antibodies and the uses thereof. The anti-ROR2 antibodies have CSASSS VSYMHWYQ, IYDTSKLAS and CQQWSSNPPTFGAG amino acid sequences of a light-chain variable region, as well as an YTITSY LMHWV, LEWIGYINPYNDGTKYNEKFKDKAT and CARSDVYYGVRFAYWGQG amino acid sequences of a heavy-chain variable region. Alternatively, the antibodies have CKASQNVGTNVAWFQ, IYLASYRYS and CQQYNSYPLTFGGG amino acid sequences of the light-chain variable region, as well as YTFTNYWIQWM, LEWIGEINPSNGRTDYNEKFKNRAT and CANYRPGYWGQG amino acid sequences of the heavy-chain variable region.
Inventors:
ZHANG SUPING (CN)
KIPPS THOMAS JAMES (CN)
WU LIUFENG (CN)
ZHANG JIANCHAO (CN)
KIPPS THOMAS JAMES (CN)
WU LIUFENG (CN)
ZHANG JIANCHAO (CN)
Application Number:
PCT/CN2019/130493
Publication Date:
July 16, 2020
Filing Date:
December 31, 2019
Export Citation:
Assignee:
UNIV SHENZHEN (CN)
International Classes:
C07K16/28; C07K14/725
Domestic Patent References:
| WO2017127702A1 | 2017-07-27 | |||
| WO2017197234A1 | 2017-11-16 | |||
| WO2016142768A1 | 2016-09-15 |
Foreign References:
| TW201831505A | 2018-09-01 |
Other References:
DATABASE GenBank 16 October 2017 (2017-10-16), ANONYMOUS: "Immunoglobulin Light Chain Variable Region, partial [Mus musculus", XP009522416, Database accession no. ATI98222.1
DATABASE GenBank 25 July 2016 (2016-07-25), ANONYMOUS: "Immunoglobulin Variable Region, partial [Mus musculus domesticus", XP055723870, Database accession no. CAA80101
DEBEBE ZRATHMELL W K: "Ror2 as a Therapeutic Target in Cancer [J", PHARMACOLOGY & THERAPEUTICS, vol. 150, 2015, pages 143 - 148, XP055358520, DOI: 10.1016/j.pharmthera.2015.01.010
See also references of EP 3922646A4
DATABASE GenBank 25 July 2016 (2016-07-25), ANONYMOUS: "Immunoglobulin Variable Region, partial [Mus musculus domesticus", XP055723870, Database accession no. CAA80101
DEBEBE ZRATHMELL W K: "Ror2 as a Therapeutic Target in Cancer [J", PHARMACOLOGY & THERAPEUTICS, vol. 150, 2015, pages 143 - 148, XP055358520, DOI: 10.1016/j.pharmthera.2015.01.010
See also references of EP 3922646A4
Attorney, Agent or Firm:
CENFO INTELLECTUAL PROPERTY AGENCY (CN)
Download PDF:
Previous Patent: DETECTION OF MALIGNANT TUMOR CELLS ANTIBODIES AND USES THEREOF
Next Patent: ELECTRIC HAIR DRYER THAT IS COMFORTABLE TO USE
Next Patent: ELECTRIC HAIR DRYER THAT IS COMFORTABLE TO USE