Title:
DIBROMOBENZYL DERIVATIVE, STEREOISOMER OR SALT THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/012698
Kind Code:
A1
Abstract:
Disclosed is a dibromobenzyl derivative having a structure represented by formula I, a stereoisomer or a pharmaceutically acceptable salt thereof, and the preparation method therefor and use thereof. The dibromobenzyl derivative and the stereoisomer of same of the present invention possess improved pharmacokinetic stability in vivo and improved drug efficacy, can be used for drugs for treating the respiratory system, particularly for preparing expectorants.
Inventors:
CEN GUODONG (CN)
YANG MAOTING (CN)
TAN SHAOJUN (CN)
YANG MAOTING (CN)
TAN SHAOJUN (CN)
Application Number:
PCT/CN2020/081092
Publication Date:
January 28, 2021
Filing Date:
March 25, 2020
Export Citation:
Assignee:
CHENGDU SHIBEIKANG BIOMEDICAL TECH CO LTD (CN)
International Classes:
C07C211/52; A61K31/137; A61P11/10
Foreign References:
| CN105693764A | 2016-06-22 | |||
| US3536713A | 1970-10-27 | |||
| CN101544572A | 2009-09-30 |
Other References:
DATABASE REGISTRY 28 February 2016 (2016-02-28), ANONYMOUS: "Benzenemethanamine, 2-amino-3,5-dibromo-N-cyclopentyl- (CA INDEX NAME) OTHER CA INDEX NAMES- 2-Amino-3,5-dibromo-N-cyclopentylbenzenemethanamine", XP055896678, retrieved from STN Database accession no. 1874745-62-6
Attorney, Agent or Firm:
CHENGDU JIUDING TIANYUAN INTELLECTUAL PROPERTY AGENCY LTD. (CN)
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