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Patent Searching and Data


Title:
DORAMECTIN CRYSTAL FORM A, CRYSTAL FORM B, AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/244148
Kind Code:
A1
Abstract:
The present application relates to a doramectin polymorph. Specifically, the present application relates to doramectin crystal form A, crystal form B, and a preparation method thereof. The polymorph can be obtained by dissolving doramectin in a good organic solvent, followed by adding a poor solvent to precipitate crystals, cooling, filtering, and drying. The doramectin polymorph of the present application has the remarkable characteristics of stable physical and chemical properties, high purity, excellent fluidity, excellent yield of the preparation method, and suitability for industrial production.

Inventors:
LI YALING (CN)
WU YANZI (CN)
SUN YUANJIE (CN)
WANG BIAO (CN)
ZHANG PENGLI (CN)
LI QIFENG (CN)
XIA XUELIN (CN)
LIU AILING (CN)
LI SHOUJUN (CN)
Application Number:
PCT/CN2019/117678
Publication Date:
December 10, 2020
Filing Date:
November 12, 2019
Export Citation:
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Assignee:
TIANJIN RINGPU BIO TECH CO LTD (CN)
RINGPU TIANJIN BIO PHARM CO LTD (CN)
International Classes:
C07H17/08; C07H1/06
Foreign References:
CN104418927A2015-03-18
CN109651465A2019-04-19
CN108976270A2018-12-11
CN110256515A2019-09-20
Attorney, Agent or Firm:
BEYOND ATTORNEYS AT LAW (CN)
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