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Title:
DRUG FOR IMPROVING FLUID RETENTION IN ACUTE HEART FAILURE
Document Type and Number:
WIPO Patent Application WO/2021/049612
Kind Code:
A1
Abstract:
The present invention pertains to a drug for improving fluid retention in acute heart failure, the drug containing an SGLT2 inhibitor.

Inventors:
KINUGAWA KOICHIRO (JP)
JOHO SHUJI (JP)
NAKAGAITO MASAKI (JP)
Application Number:
PCT/JP2020/034463
Publication Date:
March 18, 2021
Filing Date:
September 11, 2020
Export Citation:
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Assignee:
NATIONAL UNIV CORPORATION UNIV OF TOYAMA (JP)
MITSUBISHI TANABE PHARMA CORP (JP)
International Classes:
A61K45/00; A61K31/381; A61K31/382; A61K31/7028; A61K31/7034; A61K31/7048; A61K31/7056; A61P7/10; A61P9/04; A61P43/00
Foreign References:
JP2017186353A2017-10-12
JP2019508453A2019-03-28
Other References:
BUTLER JAVED, SAVARESE GIANLUIGI, SATTAR NAVEED, JANUZZI JAMES, VERMA SUBODH, LUND LARS H, FITCHETT DAVID, ZELLER CORDULA, GEORGE : "Empagliflozin is associated with a lower risk of post- acute heart failure rehospitalization and mortality: insights from the empa- reg outcome trial", JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, vol. 73, no. 9, March 2019 (2019-03-01), pages 663, XP055806058
YASUYUKI CHIBA MD, KAZUYA YONEZAWA, MASAHUMI HIMENO, MIDORI YUKINO, KYO SHIMAZU, SHOGO IMAGAWA, KAORU KOMURO, NORIKO KIMURA, TEISU: "Left ventricular noncompaction with intractable heart failure responsive to empagliflozin", JOURNAL OF CARDIOLOGY CASES, vol. 18, no. 6, 2018, pages 192 - 196, XP055806060
TAKAGI,ATSUTOSHI ET AL.,: ""A case in which an SGLT2 inhibitor was effective in acute heart failure treatment with diabetes".", ABSTRACTS OF ANNUAL SCIENTIFIC SESSION OF THE JAPANESE COLLEGE OF CARDIOLOGY : LECTURE ABSTRACTS OF JAPANESE COLLEGE OF CARDIOLOGY), vol. 64, 2016, pages P-306
NOMOTO, KAZUMIKI,: ""Efficacy of canagliflozin for acute heart failure with Diabetes",", ABSTRACTS OF ANNUAL SCIENTIFIC SESSION OF THE JAPANESE COLLEGE OF CARDIOLOGY : LECTURE ABSTRACTS OF JAPANESE COLLEGE OF CARDIOLOGY, vol. 64, 2016, pages P-481
TAKAHIRO KAMBARA; REI SHIBATA; HIROYUKI OSANAI; YOSHIHITO NAKASHIMA; HIROSHI ASANO; TOYOAKI MUROHARA; MASAYOSHI AJIOKA: "Importance of sodium-glucose cotransporter 2 inhibitor use in diabetic patients with acute heart failure", THERAPEUTIC ADVANCES IN CARDIOVASCULAR DISEASE, vol. 13, December 2019 (2019-12-01), pages 1 - 10, XP055694508
GROENEWEGEN AMY, RUTTEN FRANS H.: "Sodium-glucose co-transporter 2 inhibitors and acute heart failure", EUROPEAN JOURNAL OF HEART FAILURE, vol. 22, no. 4, April 2020 (2020-04-01), pages 723 - 725, XP055806065
DAMMAN KEVIN, BEUSEKAMP JOOST C., BOORSMA EVA M., SWART HENK P., SMILDE TOM D.J., ELVAN ARIF, ECK J.W. MARTIJN, HEERSPINK HIDDO J.: "Randomized, double-blind, placebo-controlled, multicentre pilot study on the effects of empagliflozin onclinical outcomes in patients with acute decompensated heart failure (EMPA-RESPONSE-AHF", EUROPEAN JOURNAL OF HEART FAILURE, vol. 22, no. 4, January 2020 (2020-01-01), pages 713 - 722, XP055806067
Attorney, Agent or Firm:
IP FIRM SHUWA (JP)
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