ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF - SINGULAR GENOMICS SYSTEMS INC

Title:

ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF

Document Type and Number:

WIPO Patent Application WO/2021/173711

Kind Code:

A3

Abstract:

Provided herein are modified Archaeal family B polymerases derived from species of the Archaeal microorganism Pyrococcus that exhibit improved incorporation of nucleotide analogues utilized in DNA sequencing.

Inventors:

NAJI SOUAD (US)
GLEZER ELI (US)
CHO YOUNGJIN (US)
TERRANOVA ZACHARY (US)
ABDU ABREHET (US)

Application Number:

PCT/US2021/019466

Publication Date:

September 23, 2021

Filing Date:

February 24, 2021

Export Citation:

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Assignee:

SINGULAR GENOMICS SYSTEMS INC (US)

International Classes:

C07H21/04; C12Q1/6869; C12N9/12; C12P19/34

Domestic Patent References:

WO2009131919A2	2009-10-29
WO2018148723A1	2018-08-16

Attorney, Agent or Firm:

REY, Gertrud et al. (US)

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