Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
ENZYME AND METHOD OF PRODUCTION THEREFOR
Document Type and Number:
WIPO Patent Application WO/2012/105565
Kind Code:
A1
Abstract:
Provided are a novel PLA1 and a method of production therefor. The enzyme hydrolyzes, with priority, the acyl group at the sn-1 position of a phospholipid to generate one or more of the following: a lysophospholipid, glycerol-3-phosphate, and a glycerol-3-phosphoric ester compound. The enzyme contains any one of the polypeptides described in (a) to (c) below. (a) a polypeptide having the amino acid sequence represented by SEQ ID NO:2. (b) a polypeptide having an amino acid sequence obtained by substituting, inserting, deleting and/or adding one or more amino acids in the amino acid sequence represented by SEQ ID NO:2, (c) a polypeptide having at least 75% homology with the amino acid sequence represented by SEQ ID NO:2. Thus, it is possible to provide a novel phospholipase A1 having high enzymatic activity. The PLA1 has substrate specificity with respect to phospholipids.

Inventors:
SUGIMORI DAISUKE (JP)
KANO KOTA (JP)
Application Number:
PCT/JP2012/052159
Publication Date:
August 09, 2012
Filing Date:
January 31, 2012
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
NAT UNIVERSITY CORP FUKUSHIMA UNIVERSITY (JP)
SUGIMORI DAISUKE (JP)
KANO KOTA (JP)
International Classes:
C12N15/09; C12N9/16
Foreign References:
JP2002291487A2002-10-08
JP2000060576A2000-02-29
JPH10513343A1998-12-22
Other References:
DATABASE UNIPROTKB [online] 30 November 2011 (2011-11-30), FISCHBACH M ET AL., retrieved from http://www.uniprot.org/ uniprot/D6BAL1.txt?version=4 Database accession no. D6BAL1
Attorney, Agent or Firm:
NISHIKAWA, Yoshikiyo et al. (JP)
Yoshikiyo Nishikawa (JP)
Download PDF:
Claims:



 
Previous Patent: COMBINE

Next Patent: NONWOVEN FABRIC AND TEXTILE PRODUCT