Title:
EVALUATION METHOD, CALCULATION METHOD, EVALUATION DEVICE, CALCULATION DEVICE, EVALUATION PROGRAM, CALCULATION PROGRAM, RECORDING MEDIUM, EVALUATION SYSTEM, AND TERMINAL DEVICE FOR PHARMACOLOGICAL ACTION OF IMMUNE CHECK POINT INHIBITOR
Document Type and Number:
WIPO Patent Application WO/2021/090941
Kind Code:
A1
Abstract:
The present invention addresses the problem of providing an evaluation method capable of providing highly reliable information which can be a reference to finding individual differences in the expression of the pharmacological action of an immune check point inhibitor. The present embodiment evaluates the pharmacological action of the immune check point inhibitor in a subject under evaluation by using a concentration value of at least one metabolite among Glu, Arg, Orn, Cit, His, Val, Phe, Tyr, Met, Pro, Asn, Leu, Lys, Thr, Ile, Gln, Ala, Ser, a-ABA, Trp, Gly, AnthA, hAnthA, hIAA, hKyn, hTrp, IAA, ILA, Kyn, KynA, NFKyn, NP, PA, QA, Serot and XA in the blood of the subject to be evaluated.
Inventors:
KARAKAWA SACHISE (JP)
TAGAMI TOMOYUKI (JP)
NISHIMOTO RUMI (JP)
KIKUCHI SHINYA (JP)
IMAIZUMI AKIRA (JP)
AZUMA KOICHI (JP)
HOSHINO TOMOAKI (JP)
TOKITO TAKAAKI (JP)
ISHII HIDENOBU (JP)
MATSUO NORIKAZU (JP)
TAGAMI TOMOYUKI (JP)
NISHIMOTO RUMI (JP)
KIKUCHI SHINYA (JP)
IMAIZUMI AKIRA (JP)
AZUMA KOICHI (JP)
HOSHINO TOMOAKI (JP)
TOKITO TAKAAKI (JP)
ISHII HIDENOBU (JP)
MATSUO NORIKAZU (JP)
Application Number:
PCT/JP2020/041614
Publication Date:
May 14, 2021
Filing Date:
November 06, 2020
Export Citation:
Assignee:
AJINOMOTO KK (JP)
International Classes:
G01N33/15; G01N33/50; G01N33/68
Domestic Patent References:
| WO2016056631A1 | 2016-04-14 | |||
| WO2018066621A1 | 2018-04-12 | |||
| WO2019207942A1 | 2019-10-31 | |||
| WO2019188354A1 | 2019-10-03 | |||
| WO2019117132A1 | 2019-06-20 |
Foreign References:
| US20190331682A1 | 2019-10-31 |
Attorney, Agent or Firm:
SAKAI INTERNATIONAL PATENT OFFICE (JP)
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