Title:
FLUORESCENT PROBE FOR ALDH3A1 DETECTION
Document Type and Number:
WIPO Patent Application WO/2018/105667
Kind Code:
A1
Abstract:
[Problem] To provide a fluorescent probe for ALDH3A1 detection which can be used in a flow cytometer applicable to living cells.
[Solution] A compound represented by general formula (1) or a salt thereof, in HPLC chromatogram measured under the following conditions, the retention time of said compound in an aldehyde form being longer than 6.9 minutes and the retention time of said compound in a carboxylic acid form being not longer than 6.9 minutes.
Inventors:
URANO YASUTERU (JP)
UENO TASUKU (JP)
TSUCHIHARA KATSUYA (JP)
YAGISHITA ATSUSHI (JP)
UENO TASUKU (JP)
TSUCHIHARA KATSUYA (JP)
YAGISHITA ATSUSHI (JP)
Application Number:
PCT/JP2017/043881
Publication Date:
June 14, 2018
Filing Date:
December 06, 2017
Export Citation:
Assignee:
UNIV TOKYO (JP)
NAT CANCER CT (JP)
NAT CANCER CT (JP)
International Classes:
C09B11/28; C09B23/00; C09B57/00
Foreign References:
| US20130150254A1 | 2013-06-13 | |||
| US20110165065A1 | 2011-07-07 | |||
| CN103333185A | 2013-10-02 |
Other References:
JING, BINGWEN ET AL.: "Fluorescein-fullerene dyads: a new kind of fullerene dyad-synthesis and their photophysical properties", TETRAHEDRON LETTERS, vol. 41, 2000, pages 8559 - 8563, XP004236122
JING, BINGWEN ET AL.: "Fullerene-fluorescein-anthracene hybrids: a model for artificial photosynthesis and solar energy conversion", TETRAHEDRON LETTERS, vol. 45, 2004, pages 221 - 224, XP004621851
LIU, JIAN-YONG: "Photoinduced Electron Transfer in a Distyryl BODIPY-Fullerene Dyad", CHEMISTRY-AN ASIAN JOURNAL, vol. 6, 2011, pages 174 - 179, XP055510424
KURSUNLU, AHMED NURI ET AL.: "Synthesis and spectroscopic-electrochemical properties of novel ratiometric Hg (II) chemosensor containing Bodipy and the N-phenylaza-15-crown-5 moiety", JOURNAL OF LUMINESCENCE, vol. 136, 2013, pages 430 - 436, XP055510425
JING, BINGWEN ET AL.: "Fullerene-fluorescein-anthracene hybrids: a model for artificial photosynthesis and solar energy conversion", TETRAHEDRON LETTERS, vol. 45, 2004, pages 221 - 224, XP004621851
LIU, JIAN-YONG: "Photoinduced Electron Transfer in a Distyryl BODIPY-Fullerene Dyad", CHEMISTRY-AN ASIAN JOURNAL, vol. 6, 2011, pages 174 - 179, XP055510424
KURSUNLU, AHMED NURI ET AL.: "Synthesis and spectroscopic-electrochemical properties of novel ratiometric Hg (II) chemosensor containing Bodipy and the N-phenylaza-15-crown-5 moiety", JOURNAL OF LUMINESCENCE, vol. 136, 2013, pages 430 - 436, XP055510425
Attorney, Agent or Firm:
ONO Makoto et al. (JP)
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