FLUORESCENT PROBE FOR DETECTING CARBOXYPEPTIDASE ACTIVITY

Title:

FLUORESCENT PROBE FOR DETECTING CARBOXYPEPTIDASE ACTIVITY

Document Type and Number:

WIPO Patent Application WO/2020/111279

Kind Code:

A1

Abstract:

[Problem] To provide a novel fluorescent probe for detecting carboxypeptidase activity. [Solution] A compound represented by general formula (I) or a salt thereof.

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Inventors:

URANO YASUTERU (JP)
KAMIYA MAKO (JP)
KURIKI YUGO (JP)

Application Number:

PCT/JP2019/047000

Publication Date:

June 04, 2020

Filing Date:

December 02, 2019

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Assignee:

UNIV TOKYO (JP)

International Classes:

C09K11/06; C12Q1/37; G01N21/64; G01N33/543; G01N33/68; C07F9/655; C07F9/6561

Domestic Patent References:

WO2010095450A1	2010-08-26
WO2001064664A1	2001-09-07

Foreign References:

JP2018145126A	2018-09-20
JP2014506913A	2014-03-20

Other References:

KURIKI, Y. ET AL.: "Establishment of molecular design strategy to obtain activatable fluorescent probes for carboxypeptidases", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 140, 25 January 2018 (2018-01-25), pages 1767 - 1773, XP055633935, DOI: 10.1021/jacs.7b11014

Attorney, Agent or Firm:

ONO Makoto et al. (JP)

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