FLUORINE-CONTAINING PYRIMIDINE COMPOUND AND MANUFACTURING METHOD FOR SAME

WIPO Patent Application WO/2021/085540

A1

Provided are: a novel fluorine-containing pyrimidine compound with substituents at the 4-position, the 5-position, and the 6-position and a furan ring structure as a substituent at the 2-position; and a manufacturing method by which the fluorine-containing pyrimidine compound can be easily manufactured.　A fluorine-containing pyrimidine compound represented by general formula (1) or (2). (In general formulas (1) and (2), R represents a hydrocarbon group with 1–12 carbons, X and Y each independently represent a hydrogen atom, a halogen atom, a hydrocarbon group with 1–10 carbons, -CnF2n+1 (where n is an integer from 1 to 10), a nitro group, a boric acid group, -OA1, -SOmA1 (where m is an integer from 0 to 3), -NA1A2, -COOA1, or -CONA1A2, and A1 and A2 each independently represent a hydrogen atom or a hydrocarbon group with 1–10 carbons.)

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SEINO JUNYA (JP)
AOTSU RIE (JP)
KOKIN KEISUKE (JP)

PCT/JP2020/040661

May 06, 2021

October 29, 2020

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UNIMATEC CO LTD (JP)

A61P1/18; A61K31/506; A61P9/10; A61P13/12; A61P31/04; A61P35/00; A61P35/02; A61P35/04; C07D405/04

WO2020116296A1

2020-06-11

US20150018353A1	2015-01-15
JP2007506746A	2007-03-22
CN108503623A	2018-09-07
CN108299465A	2018-07-20
CN107286146A	2017-10-24
CN108218793A	2018-06-29

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See also references of EP 4052759A4

EINSEL Felix-Reinhard et al. (JP)

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