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Title:
FORMALIZATION OF RETINAL NERVE FIBER LAYER THICKNESS MEASUREMENTS MADE BY TIME DOMAIN-OPTICAL COHERENCE TOMOGRAPHY
Document Type and Number:
WIPO Patent Application WO/2011/063220
Kind Code:
A3
Abstract:
A scan location matching (SLM) method identifies conventional time domain optical coherence tomography (TD-OCT) circle scan locations within three-dimensional spectral domain OCT scan volumes. A technique uses both the SLM algorithm and a mathematical retinal nerve fiber bundle distribution (RNFBD) model, which is a simplified version of the anatomical retinal axon bundle distribution pattern, to normalize TD-OCT thickness measurements for the retinal nerve fiber layer (RNFL) of an off-centered TD-OCT circle scan to a virtual location, centered on the optic nerve head. The RNFBD model eliminates scan- to-scan RNFL thickness measurement variation caused by manual placement of TD-OCT circle scan.

Inventors:
KIM JONG S (KR)
ISHIKAWA HIROSHI (JP)
SCHUMAN JOEL S (US)
WOLLSTEIN GADI (IL)
Application Number:
PCT/US2010/057402
Publication Date:
October 06, 2011
Filing Date:
November 19, 2010
Export Citation:
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Assignee:
UNIV PITTSBURGH (US)
KIM JONG S (KR)
ISHIKAWA HIROSHI (JP)
SCHUMAN JOEL S (US)
WOLLSTEIN GADI (IL)
International Classes:
A61B1/04; A61B3/10; G01B5/02; G01B9/02
Foreign References:
US20090073387A12009-03-19
US7347548B22008-03-25
US7139602B22006-11-21
Attorney, Agent or Firm:
BENT, Stephen, A. et al. (Washington Harbour3000 K Street, NW 6th Floo, Washington DC, US)
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