Title:
FUSION POLYPEPTIDE COMPRISING FC REGION OF IMMUNOGLOBULIN AND GDF15
Document Type and Number:
WIPO Patent Application WO/2020/218827
Kind Code:
A1
Abstract:
Disclosed are: a fusion polypeptide comprising growth/differentiation factor 15 (GDF15) and an Fc region of an immunoglobulin; a pharmaceutical composition comprising the fusion polypeptide; and a method for increasing the in vivo duration of GDF15, the method comprising a step for fusing an Fc region of an immunoglobulin.
Inventors:
KIM YEONCHUL (KR)
MIN KYEONGSIK (KR)
SON YOUNG DOK (KR)
NA KYUBONG (KR)
HONG JI HO (KR)
JUNG SAEM (KR)
JIN MYUNG WON (KR)
PARK JI A (KR)
NOH SOOMIN (KR)
MIN KYEONGSIK (KR)
SON YOUNG DOK (KR)
NA KYUBONG (KR)
HONG JI HO (KR)
JUNG SAEM (KR)
JIN MYUNG WON (KR)
PARK JI A (KR)
NOH SOOMIN (KR)
Application Number:
PCT/KR2020/005324
Publication Date:
October 29, 2020
Filing Date:
April 22, 2020
Export Citation:
Assignee:
LG CHEMICAL LTD (KR)
International Classes:
C07K14/475; A61K38/18; A61K47/68; A61P1/16; A61P3/04; A61P3/10
Foreign References:
| US20140378665A1 | 2014-12-25 | |||
| EP3144320A1 | 2017-03-22 | |||
| US20160168213A1 | 2016-06-16 | |||
| KR20190003746A | 2019-01-09 | |||
| KR20170020878A | 2017-02-24 | |||
| KR20150125402A | 2015-11-09 | |||
| KR101038126B1 | 2011-05-31 | |||
| KR101868139B1 | 2018-06-15 | |||
| KR101868139B1 | 2018-06-15 |
Other References:
KABAT, E.A. ET AL.: "Sequences of Proteins of Immunological Interest", 1991, U.S. DEPT. OF HEALTH AND HUMAN SERVICES
See also references of EP 3978518A4
See also references of EP 3978518A4
Attorney, Agent or Firm:
YOU ME PATENT AND LAW FIRM (KR)
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