Title:
GEMCITABINE DERIVATIVE, COMPOSITION CONTAINING THE DERIVATIVE AND PHARMACEUTICAL USE OF THE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2015/081867
Kind Code:
A1
Abstract:
The present invention provides a gemcitabine derivative of formula (I) and a method for preparing the same. The present invention further relates to a pharmaceutical composition comprising a pharmaceutically effective dose of the gemcitabine derivative and a pharmaceutically acceptable excipient or additive. The present invention further provides an application of the derivative in preparing antineoplastic drugs. The compound designed in the present invention is innovative in structure, and has a notable antineoplastic activity. Compound preparation raw materials involved in the present invention are wide in source and are easily obtained, the preparing method is simple and convenient, and easy in operation, and the product yield is high, which facilitates industrial mass production.
Inventors:
WU YAODONG (CN)
SHAN JIAQI (CN)
SHEN XIMING (CN)
WU CHUNXIA (CN)
HUANG BINNAN (CN)
SHAN JIAQI (CN)
SHEN XIMING (CN)
WU CHUNXIA (CN)
HUANG BINNAN (CN)
Application Number:
PCT/CN2014/093005
Publication Date:
June 11, 2015
Filing Date:
December 04, 2014
Export Citation:
Assignee:
HANGZHOU MINSHENG INST FOR PHARMA RES CO LTD (CN)
HANGZHOU MINSHENG PHARM GROUP (US)
HANGZHOU MINSHENG PHARM GROUP (US)
International Classes:
C07H19/073; A61K31/7068; A61P35/00; C07H1/00
Foreign References:
| CN1693309A | 2005-11-09 | |||
| CN101061131A | 2007-10-24 | |||
| CN102432654A | 2012-05-02 |
Other References:
See also references of EP 3078671A4
None
None
Attorney, Agent or Firm:
SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC (CN)
上海专利商标事务所有限公司 (CN)
上海专利商标事务所有限公司 (CN)
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