Title:
GLYCOLIPOPEPTIDE BIOSURFACTANTS
Document Type and Number:
WIPO Patent Application WO/2017/174748
Kind Code:
A3
Abstract:
Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine- leucinol dipeptide linked to the lipid oligomer. Such surfactants can be used to create an oil-in- water or water-in-oil emulsion by mixing together a polar component; a non-polar component; and the surfactant. Biosurfactants of the newly discovered class can be made by isolating and culturing a microorganism which produces the biosurfactant, and then isolating the biosurfactant from the culture. A microorganism can be engineered to produce biosurfactant of this newly discovered class by expressing a set of heterologous genes involved in the biosynthesis of the biosurfactant in the microorganism.
Inventors:
KERR RUSSELL GREIG (CA)
HALTLI BRADLEY ARNOLD (CA)
MARCHBANK DOUGLAS HUBERT (CA)
BERRUÉ FABRICE (CA)
HALTLI BRADLEY ARNOLD (CA)
MARCHBANK DOUGLAS HUBERT (CA)
BERRUÉ FABRICE (CA)
Application Number:
PCT/EP2017/058296
Publication Date:
November 23, 2017
Filing Date:
April 06, 2017
Export Citation:
Assignee:
CRODA INT PLC (GB)
International Classes:
C11D3/38; C02F3/34; C07H15/04; C11D1/10; C11D1/66; C12R1/01
Foreign References:
| US20130331466A1 | 2013-12-12 | |||
| US20130085067A1 | 2013-04-04 |
Other References:
ANDREA FRANZETTI ET AL: "Environmental fate, toxicity, characteristics and potential applications of novel bioemulsifiers produced by7bCT5", BIORESOURCE TECHNOLOGY, ELSEVIER BV, GB, vol. 108, 3 January 2012 (2012-01-03), pages 245 - 251, XP028460298, ISSN: 0960-8524, [retrieved on 20120110], DOI: 10.1016/J.BIORTECH.2012.01.005
DANYELLE SANTOS ET AL: "Biosurfactants: Multifunctional Biomolecules of the 21st Century", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 17, no. 3, 18 March 2016 (2016-03-18), pages 401, XP055397037, DOI: 10.3390/ijms17030401
J.-I. HAN ET AL: "Genome of the Root-Associated Plant Growth-Promoting Bacterium Variovorax paradoxus Strain EPS", GENOME ANNOUNCEMENTS, vol. 1, no. 5, 24 October 2013 (2013-10-24), pages e00843 - 13, XP055397689, DOI: 10.1128/genomeA.00843-13
DANYELLE SANTOS ET AL: "Biosurfactants: Multifunctional Biomolecules of the 21st Century", INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 17, no. 3, 18 March 2016 (2016-03-18), pages 401, XP055397037, DOI: 10.3390/ijms17030401
J.-I. HAN ET AL: "Genome of the Root-Associated Plant Growth-Promoting Bacterium Variovorax paradoxus Strain EPS", GENOME ANNOUNCEMENTS, vol. 1, no. 5, 24 October 2013 (2013-10-24), pages e00843 - 13, XP055397689, DOI: 10.1128/genomeA.00843-13
Attorney, Agent or Firm:
CLEGG, Richard et al. (GB)
Download PDF: