HDAC6 SELECTIVE INHIBITORS, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Title:

HDAC6 SELECTIVE INHIBITORS, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF

Document Type and Number:

WIPO Patent Application WO/2018/130155

Kind Code:

A1

Abstract:

Compounds serving as histone deacetylase 6 (HDAC6) selective inhibitors, and applications thereof in the preparation of drugs for treating HDAC6-related diseases. Specifically disclosed are a compound as represented by formula (I) and a pharmaceutically acceptable salt thereof.

Inventors:

WU HAO (CN)
WEI CHANGQING (CN)
GUO QIANG (CN)
ZHANG GUIFEN (CN)
LIU BIN (CN)
LIAO YONGGANG (CN)
XIAO YAO (CN)
CHEN SHUHUI (CN)

Application Number:

PCT/CN2018/072088

Publication Date:

July 19, 2018

Filing Date:

January 10, 2018

Export Citation:

Click for automatic bibliography generation Help

Assignee:

MEDSHINE DISCOVERY INC (CN)

International Classes:

C07D211/86; A61K31/16; A61K31/34; A61K31/435; A61P35/00; C07D307/04; C07D309/04; C07D405/04; C07D405/14

Domestic Patent References:

WO2011106632A1	2011-09-01
WO2015100363A1	2015-07-02
WO2015007870A1	2015-01-22

Foreign References:

CN103429574A	2013-12-04
CN101641338A	2010-02-03

Other References:

DRUG DESIGN, DEVELOPMENT AND THERAPY, vol. 10, 2016, pages 217 - 226
BERGE ET AL.: "Pharmaceutical Salts", JOURNAL OF PHARMACEUTICAL SCIENCE, vol. 66, 1977, pages 1 - 19, XP002675560, doi:10.1002/jps.2600660104
See also references of EP 3569592A4

Attorney, Agent or Firm:

SHANGHAI BESHINING LAW OFFICE (CN)

Download PDF:

View/Download PDF PDF Help

Previous Patent: HIGH POWER MASS DENSITY LINEAR DRIVING DEVICE OF SIMPLIFIED STRUCTURE

Next Patent: WINDOWED CIRCUIT BOARD DEVICE AND MANUFACTURING METHOD THEREFOR, AND CIRCUIT BOARD DEVICE EMBEDDING ...