Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
HER2 ANTIBODY AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/127889
Kind Code:
A1
Abstract:
An antibody or antigen-binding fragment specifically binding to HER2, a multi-specific antigen binding molecule, a chimeric antigen receptor, an immune effector cell, a nucleic acid fragment, a vector, a host cell, a pharmaceutical composition, a kit, a preparation method, and an application thereof in treatment of tumors or cancers and detection of HER2, which is of great significance for the development of HER2 antibody therapeutic drugs and detection reagents.

More Like This:
Inventors:
SHAO XIAOHUI (CN)
YANG CUIQING (CN)
CAO ZHUOXIAO (CN)
TANG RENHONG (CN)
REN JINSHENG (CN)
Application Number:
PCT/CN2021/139018
Publication Date:
June 23, 2022
Filing Date:
December 17, 2021
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
JIANGSU SIMCERE PHARM CO LTD (CN)
International Classes:
C07K16/30; A61K39/395; A61P35/00; C07K16/28
Domestic Patent References:
WO2010130677A12010-11-18
WO2014198748A12014-12-18
Foreign References:
US20110059090A12011-03-10
CN109096401A2018-12-28
CN111825767A2020-10-27
CN109627319A2019-04-16
CN102321175A2012-01-18
CN101037475A2007-09-19
Other References:
KIJANKA M; VAN DONSELAAR E G; MÜLLER W H; DORRESTEIJN B; POPOV-ČELEKETIĆ D; EL KHATTABI M; VERRIPS C T; VAN BERGEN EN HENEGOUWEN P: "A novel immuno-gold labeling protocol for nanobody-based detection of HER2 in breast cancer cells using immuno-electron microscopy", JOURNAL OF STRUCTURAL BIOLOGY, vol. 199, no. 1, 25 May 2017 (2017-05-25), United States , pages 1 - 11, XP085067096, ISSN: 1047-8477, DOI: 10.1016/j.jsb.2017.05.008
WU XIAOQIONG, CHEN SIQI, LIN LIMIN, LIU JIAYU, WANG YANLAN, LI YUMEI, LI QING, WANG ZHONG: "A Single Domain–Based Anti-Her2 Antibody Has Potent Antitumor Activities", TRANSLATIONAL ONCOLOGY, vol. 11, no. 2, 1 April 2018 (2018-04-01), United States , pages 366 - 373, XP055942548, ISSN: 1936-5233, DOI: 10.1016/j.tranon.2018.01.024
HUSSACK GREG, RAPHAEL SHALINI, LOWDEN MICHAEL J., HENRY KEVIN A.: "Isolation and characterization of camelid single-domain antibodies against HER2", BMC RESEARCH NOTES, vol. 11, no. 1, 1 December 2018 (2018-12-01), pages 1 - 5, XP055942553, DOI: 10.1186/s13104-018-3955-8
WANG LAN-DONG, LIU FENG;CHENG YAN;LI DA-LEI;HAN BING;ZHANG SHU-MIN;FENG DONG-XIAO: "Generation of an alpaca derived nanobody recognizing human Her2 antigen", MILITARY MEDICAL SCIENCES, vol. 41, no. 3, 25 March 2017 (2017-03-25), CN , pages 184 - 189, XP055942561, ISSN: 1674-9960, DOI: 10.7644/j.issn.1674-9960.2017.03.006
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
Download PDF: