HETEROCYCLIC COMPOUNDS AS INHIBITORS OF HPK1 - GUANGDONG NEWOPP BIOPHARMACEUTICALS CO LTD

Title:

HETEROCYCLIC COMPOUNDS AS INHIBITORS OF HPK1

Document Type and Number:

WIPO Patent Application WO/2021/004547

Kind Code:

A1

Abstract:

This disclosure relates to heterocyclics as inhibitors of HPK1, in particular relates to a compound of Formula I or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising said compound that useful for treatment of HPK1 mediated diseases and conditions such as cancer. (I)

Inventors:

WANG ZHAOYIN (CN)
LI NANXIN (US)
SHAO YANQIANG (CN)
LI LINTONG (US)

Application Number:

PCT/CN2020/101711

Publication Date:

January 14, 2021

Filing Date:

July 13, 2020

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Assignee:

GUANGDONG NEWOPP BIOPHARMACEUTICALS CO LTD (CN)

International Classes:

C07D417/14; A61K31/4375; A61K31/498; A61P35/00; C07D401/14; C07D471/04; C07D487/04

Domestic Patent References:

WO2018183964A1	2018-10-04
WO2019089835A1	2019-05-09
WO2019079626A1	2019-04-25
WO2017189829A1	2017-11-02
WO2017189823A2	2017-11-02
WO2007125405A2	2007-11-08

Attorney, Agent or Firm:

XU & PARTNERS, LLC. (CN)

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