Title:
HETEROCYCLIC DERIVATIVE HAVING β2 RECEPTOR AGITATION AND M RECEPTOR ANTAGONISTIC ACTIVITY AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2020/244452
Kind Code:
A1
Abstract:
A heterocyclic derivative having a β2 receptor agitation and M receptor antagonistic activity and medical use thereof. The heterocyclic derivative is a compound represented by general formula (I) or a mesomer, racemate, enantiomer, diastereoisomer thereof, or a mixture form thereof, or a prodrug thereof, or a pharmaceutically acceptable salt thereof. The present invention further provides the preparation method therefor, a pharmaceutical composition containing the heterocyclic derivative, and an application in the preparation of a drug for treating airway obstructive diseases.
Inventors:
YIN HUIJUN (CN)
YAN XU (CN)
SHA HANMING (CN)
LIU GUOBIAO (CN)
SI CHUNFENG (CN)
YAN XU (CN)
SHA HANMING (CN)
LIU GUOBIAO (CN)
SI CHUNFENG (CN)
Application Number:
PCT/CN2020/093214
Publication Date:
December 10, 2020
Filing Date:
May 29, 2020
Export Citation:
Assignee:
THE NATIONAL INSTITUTES OF PHARMACEUTICAL RES AND DEVELOPMENT NIP (CN)
International Classes:
C07D215/26; A61P11/00; C07D277/68; C07D405/12; C07D409/14; C07D417/12; C07D417/14
Domestic Patent References:
| WO2018150347A1 | 2018-08-23 | |||
| WO2017012489A1 | 2017-01-26 | |||
| WO2008096127A2 | 2008-08-14 | |||
| WO2011141180A1 | 2011-11-17 | |||
| WO2015011244A1 | 2015-01-29 | |||
| WO2014131851A1 | 2014-09-04 | |||
| WO2015011245A1 | 2015-01-29 | |||
| WO2008149110A1 | 2008-12-11 | |||
| WO2016180348A1 | 2016-11-17 | |||
| WO2018150347A1 | 2018-08-23 |
Foreign References:
| CN104024245A | 2014-09-03 | |||
| CN106336406A | 2017-01-18 |
Attorney, Agent or Firm:
GE CHENG & CO. LTD. (CN)
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