Title:
HETEROCYCLIC NITROGEN COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/057256
Kind Code:
A1
Abstract:
The present invention falls within the field of medicinal chemistry, and relates to a heterocyclic nitrogen compound, and a pharmaceutical composition containing same, a preparation method therefor and a use thereof. In particular, provided in the present invention is a compound of the structure of formula II, which compound has a significant NLRP3 regulation effect, can be used as an efficient NLRP3 regulator, and has an anti-tumour activity.
Inventors:
YOU ZEJIN (CN)
HE YUN (CN)
TIAN QIANG (CN)
SONG HONGMEI (CN)
XUE TONGTONG (CN)
WANG JINGYI (CN)
HE YUN (CN)
TIAN QIANG (CN)
SONG HONGMEI (CN)
XUE TONGTONG (CN)
WANG JINGYI (CN)
Application Number:
PCT/CN2020/106080
Publication Date:
April 01, 2021
Filing Date:
July 31, 2020
Export Citation:
Assignee:
SICHUAN KELUN BIOTECH BIOPHARMACEUTICAL CO LTD (CN)
International Classes:
C07D495/04; A61K31/4365; A61K31/444; A61P35/00
Domestic Patent References:
WO2020168927A1 | 2020-08-27 | |||
WO2018235966A1 | 2018-12-27 |
Foreign References:
EP1724268A1 | 2006-11-22 | |||
CN1280580A | 2001-01-17 | |||
CN1671714A | 2005-09-21 | |||
CN104936963A | 2015-09-23 | |||
CN1714092A | 2005-12-28 | |||
CN1993129A | 2007-07-04 |
Attorney, Agent or Firm:
LINDA LIU & PARTNERS (CN)
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