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Title:
HIGH THROUGHPUT MICROBALANCE AND METHODS OF USING SAME
Document Type and Number:
WIPO Patent Application WO2003100390
Kind Code:
A3
Abstract:
A method and apparatus for measurement of mass of small sample sizes. The method and apparatus is particularly adapted for providing microbalance measurement of solid materials as part of a combinatorial research program. The method and apparatus contemplate a system (100) including one resonator, or a plurality of resonators in a resonator array (110), adapted to monitor the response of a sample to a change in environmental condition, and correlating the response with mass change in the samples.

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Inventors:
CARLSON ERIC D (US)
KOLOSOV OLEG (US)
MATSIEV LEONID (US)
MAZZOLA LAURA T (US)
SPITKOVSKY MIKHAIL (US)
GALLIPEO JOHN (US)
Application Number:
PCT/US2003/012503
Publication Date:
February 05, 2004
Filing Date:
April 23, 2003
Export Citation:
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Assignee:
SYMYX TECHNOLOGIES INC (US)
CARLSON ERIC D (US)
KOLOSOV OLEG (US)
MATSIEV LEONID (US)
MAZZOLA LAURA T (US)
SPITKOVSKY MIKHAIL (US)
GALLIPEO JOHN (US)
International Classes:
G01G3/13; G01N5/04; G01N33/15; (IPC1-7): G01N5/04; G01G3/16; B01J19/00; G01N27/00
Domestic Patent References:
WO2001077624A22001-10-18
WO2002012265A12002-02-14
WO1999018431A11999-04-15
WO2003014732A12003-02-20
Foreign References:
EP0779510A21997-06-18
US5661233A1997-08-26
US5776359A1998-07-07
Other References:
SMITH A L ET AL: "Water sorption isotherms and enthalpies of water sorption by lysozyme using the quartz crystal microbalance/heat conduction calorimeter", BIOCHIMICA ET BIOPHYSICA ACTA. PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, ELSEVIER, AMSTERDAM,, NL, vol. 1594, no. 1, 31 January 2002 (2002-01-31), pages 150 - 159, XP004334750, ISSN: 0167-4838
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