Title:
HIGHLY ABSORPTIVE ORAL TYROSINE FORMULATION
Document Type and Number:
WIPO Patent Application WO/2019/059356
Kind Code:
A1
Abstract:
Provided is a tyrosine formulation having excellent bio-absorbability of tyrosine when orally ingested. This oral formulation contains glycyl tyrosine, a salt thereof, or a solvate thereof and has an improved bio-absorbability of tyrosine.
Inventors:
TAMURA KOTARO (JP)
IWASHITA MASAZUMI (JP)
MINEGISHI YOSHIHIKO (JP)
IWASHITA MASAZUMI (JP)
MINEGISHI YOSHIHIKO (JP)
Application Number:
PCT/JP2018/035086
Publication Date:
March 28, 2019
Filing Date:
September 21, 2018
Export Citation:
Assignee:
KAO CORP (JP)
International Classes:
A23L33/18; A61K38/05; A61P25/00; A61P43/00
Domestic Patent References:
WO2009038106A1 | 2009-03-26 | |||
WO2011078324A1 | 2011-06-30 |
Foreign References:
JP2003063959A | 2003-03-05 | |||
JPH07149665A | 1995-06-13 |
Other References:
ESAKI, K. ET AL.: "Increased Tyrosine in the Brain and Serum of Mice by Orally Administering Dipeptide SY", BIOSCI. BIOTECHNOL. BIOCHEM., vol. 77, no. 4, 2013, pages 847 - 849, XP055584370, ISSN: 0916-8451, DOI: 10.1271/bbb.120747
MAHER, T. J. ET AL.: "Use of Parenteral Dipeptides To Increase Serum Tyrosine Levels and To Enhance Catecholamine-Mediated Neurotransmission", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 79, no. 8, 1990, pages 685 - 687, XP055094176, ISSN: 0022-3549, DOI: doi:10.1002/jps.2600790807
MAHER, T. J. ET AL.: "Use of Parenteral Dipeptides To Increase Serum Tyrosine Levels and To Enhance Catecholamine-Mediated Neurotransmission", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 79, no. 8, 1990, pages 685 - 687, XP055094176, ISSN: 0022-3549, DOI: doi:10.1002/jps.2600790807
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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