Title:
HUMAN RECEPTOR PROTEINS; RELATED REAGENTS AND METHODS
Document Type and Number:
WIPO Patent Application WO2001090151
Kind Code:
A3
Abstract:
Nucleic acids encoding mammalian, e.g., human receptors, purified receptor proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the compositions for both diagnostic and therapeutic utilities are provided.
Inventors:
HARDIMAN GERARD T
ROCK FERNANDO L
BAZAN J FERNANDO
KASTELEIN ROBERT A
HO STEPHEN W K
LIU YONG-JUN
ROCK FERNANDO L
BAZAN J FERNANDO
KASTELEIN ROBERT A
HO STEPHEN W K
LIU YONG-JUN
Application Number:
PCT/US2001/016766
Publication Date:
October 17, 2002
Filing Date:
May 23, 2001
Export Citation:
Assignee:
SCHERING CORP (US)
International Classes:
A61K38/00; A61P37/00; A61P43/00; C07K14/705; C07K14/715; C07K16/28; C07K19/00; C12N1/15; C12N15/09; C12N1/19; C12N1/21; C12N5/10; C12N15/12; C12P21/02; C12P21/08; C12Q1/02; F02D11/10; (IPC1-7): C07K14/705; C07K16/28; C12N15/12; C12N15/62; A61K38/17; A61K39/395; C12N5/10; C12N1/21
Domestic Patent References:
| WO1998050547A2 | 1998-11-12 | |||
| WO1999020756A2 | 1999-04-29 |
Other References:
ROCK FERNANDO L ET AL: "A family of human receptors structurally related to Drosophila toll.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 95, no. 2, 20 January 1998 (1998-01-20), Jan. 20, 1998, pages 588 - 593, XP002197052, ISSN: 0027-8424
CHAUDHARY PREET M ET AL: "Cloning and characterization of two toll/interleukin-1 receptor-like genes TIL3 and TIL4: Evidence for a multi-gene receptor family in humans.", BLOOD, vol. 91, no. 11, 1 June 1998 (1998-06-01), pages 4020 - 4027, XP002197053, ISSN: 0006-4971
CHAUDHARY PREET M ET AL: "Cloning and characterization of two toll/interleukin-1 receptor-like genes TIL3 and TIL4: Evidence for a multi-gene receptor family in humans.", BLOOD, vol. 91, no. 11, 1 June 1998 (1998-06-01), pages 4020 - 4027, XP002197053, ISSN: 0006-4971
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