Title:
HYDROGELS AND METHODS FOR THEIR PRODUCTION
Document Type and Number:
WIPO Patent Application WO2001077197
Kind Code:
A3
Abstract:
The present invention relates to new hydrogels with improved mechanical properties and methods of their preparation. The hydrogels are formed from hydrophilic polymers having function hydroxyl groups and have low elasticity modulus typically less than about 10 kPa, a tensile strength above 1 MPa, an elongation above 50 % which makes suitable as medical implants, in particular intraocular lenses. The hydrogels are prepared by a crosslinking method with a comparatively low concentration of hydrophilic polymer of a sufficiently high molecular weight dissolved in a good solvent.
Inventors:
PENNINGS ALBERT JOHAN (BE)
SPAANS COENRAD JAN (NL)
DE GROOT JACQUELINE HERMINA (NL)
SPAANS COENRAD JAN (NL)
DE GROOT JACQUELINE HERMINA (NL)
Application Number:
PCT/EP2001/004010
Publication Date:
April 11, 2002
Filing Date:
April 06, 2001
Export Citation:
Assignee:
PHARMACIA GRONINGEN BV (NL)
PENNINGS ALBERT JOHAN (BE)
SPAANS COENRAD JAN (NL)
GROOT JACQUELINE HERMINA DE (NL)
PENNINGS ALBERT JOHAN (BE)
SPAANS COENRAD JAN (NL)
GROOT JACQUELINE HERMINA DE (NL)
International Classes:
A61L27/16; A61L27/52; A61L27/00; C08F8/30; C08F261/00; C08F261/04; C08F283/00; C08G18/62; C08G59/62; C08G85/00; (IPC1-7): C08F8/30; G02B1/04
Domestic Patent References:
| WO1996040810A1 | 1996-12-19 |
Foreign References:
| EP0530140A1 | 1993-03-03 | |||
| EP0256139A1 | 1988-02-24 | |||
| US4598122A | 1986-07-01 | |||
| EP0473553A2 | 1992-03-04 | |||
| US4670506A | 1987-06-02 | |||
| EP0216074A2 | 1987-04-01 | |||
| US5744816A | 1998-04-28 | |||
| US2887469A | 1959-05-19 |
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