Title:
HYDROLYSIS OF MANNOSE-1-PHOSPHO-6-MANNOSE LINKAGE TO PHOSPHO-6-MANNOSE
Document Type and Number:
WIPO Patent Application WO/2011/039634
Kind Code:
A9
Abstract:
Described herein are methods and genetically engineered cells useful for uncapping a mannose- 6 -phosphate residue on an oligosaccharide by using a mannosidase capable of hydrolyzing mannose- 1 -phospho- 6 -mannose linkage to phospho - 6 -mannose.
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Inventors:
CALLEWAERT NICO LUC MARC (BE)
VERVECKEN WOUTER (BE)
TIELS PETRA SOPHIE (BE)
REMAUT HAN KAREL (BE)
PIENS KATHLEEN CAMILLA TELESPHORE ALIDA MARIA (BE)
VERVECKEN WOUTER (BE)
TIELS PETRA SOPHIE (BE)
REMAUT HAN KAREL (BE)
PIENS KATHLEEN CAMILLA TELESPHORE ALIDA MARIA (BE)
Application Number:
PCT/IB2010/002589
Publication Date:
November 10, 2011
Filing Date:
September 29, 2010
Export Citation:
Assignee:
UNIV GENT (BE)
VIB VZW (BE)
OXYRANE UK LTD (GB)
UNIV BRUXELLES (BE)
CALLEWAERT NICO LUC MARC (BE)
VERVECKEN WOUTER (BE)
TIELS PETRA SOPHIE (BE)
REMAUT HAN KAREL (BE)
PIENS KATHLEEN CAMILLA TELESPHORE ALIDA MARIA (BE)
VIB VZW (BE)
OXYRANE UK LTD (GB)
UNIV BRUXELLES (BE)
CALLEWAERT NICO LUC MARC (BE)
VERVECKEN WOUTER (BE)
TIELS PETRA SOPHIE (BE)
REMAUT HAN KAREL (BE)
PIENS KATHLEEN CAMILLA TELESPHORE ALIDA MARIA (BE)
International Classes:
C12N9/24; C07H11/04; C12P19/14
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