Title:
Γ-HYDROXYBUTYRIC-ACID-BASED COMPOUND-SENSITIVE CHROMOGENIC COMPOUND, AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/146086
Kind Code:
A1
Abstract:
The present invention relates to: a compound that is sensitive to γ-hydroxybutyric acid (GHB)-based compounds, and thus changes color; and an application thereof, and since the GHB-based compound-sensitive chromogenic compound of the present invention changes color within a very short time (several seconds) even in an environment in which a very low concentration of GHB-based compounds are present, the GHB-based compounds can be immediately detected without the introduction of a separate additional process and equipment, and thus narcotic drugs including GHB-based compounds can be readily detected on-site and in real time even with the naked eyes.
Inventors:
KWON OH SEOK (KR)
PARK CHUL SOON (KR)
KIM KYUNG HO (KR)
KIM SOOMIN (KR)
KIM JIN YEONG (KR)
PARK SEON JOO (KR)
SEO SEONG EUN (KR)
LEE JIYEON (KR)
HA SIYOUNG (KR)
PARK CHUL SOON (KR)
KIM KYUNG HO (KR)
KIM SOOMIN (KR)
KIM JIN YEONG (KR)
PARK SEON JOO (KR)
SEO SEONG EUN (KR)
LEE JIYEON (KR)
HA SIYOUNG (KR)
Application Number:
PCT/KR2021/020313
Publication Date:
July 07, 2022
Filing Date:
December 30, 2021
Export Citation:
Assignee:
KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR)
International Classes:
C07D277/64; C07D209/10; C07D263/56; C09B62/002; G01N21/64; G01N21/78; G01N31/22; G01N33/58; G01N33/94
Foreign References:
| DE10255894A1 | 2004-06-17 | |||
| KR20040010840A | 2004-01-31 | |||
| CN109912532A | 2019-06-21 |
Other References:
KRIEG REIMAR, HALBHUBER KARL-JÜRGEN: "Novel Oxidative Self-Anchoring Fluorescent Substrates for the Histochemical Localization of Endogenous and Immunobound Peroxidase Activity", JOURNAL OF MOLECULAR HISTOLOGY, SPRINGER-VERLAG, DORDRECHT, NL, vol. 35, no. 5, 1 June 2003 (2003-06-01), NL , pages 471 - 487, XP055947419, ISSN: 1567-2379, DOI: 10.1023/B:HIJO.0000045946.02035.e8
VAN RIESEN ABIGAIL J., JOHNSON RYAN E., AL-ABDUL-WAHID M. SAMEER, LIOTA CRISTINA, CHRISTYANTON ANJELYN, MANDERVILLE RICHARD A.: "Temperature Sensing of Thiolate Addition by Phenolate Merocyanine Dyes: Importance of the Quinone Methide Resonance Structure", THE JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 86, no. 2, 15 January 2021 (2021-01-15), pages 1583 - 1590, XP055947421, ISSN: 0022-3263, DOI: 10.1021/acs.joc.0c02428
VAN RIESEN ABIGAIL J., JOHNSON RYAN E., AL-ABDUL-WAHID M. SAMEER, LIOTA CRISTINA, CHRISTYANTON ANJELYN, MANDERVILLE RICHARD A.: "Temperature Sensing of Thiolate Addition by Phenolate Merocyanine Dyes: Importance of the Quinone Methide Resonance Structure", THE JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 86, no. 2, 15 January 2021 (2021-01-15), pages 1583 - 1590, XP055947421, ISSN: 0022-3263, DOI: 10.1021/acs.joc.0c02428
Attorney, Agent or Firm:
ECM IP & LAW FIRM (KR)
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