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Title:
INHIBITORS OF FACTOR Xa
Document Type and Number:
WIPO Patent Application WO2000071511
Kind Code:
A3
Abstract:
Compounds of the formula A - Y - D - E - G - J - Z - L in which D is a direct link, a substituted or unsubstituted phenyl or naphtyl group or a heterocyclic ring system; Z is a substituted or unsubstituted phenyl or naphthyl group or a heterocyclic ring system; and the other variables are as defined in the claims, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.

Inventors:
SU TING
ZHU BING-YAN
KANE-MAGUIRE KIM
SCARBOROUGH ROBERT M
ZHANG PENGLIE
Application Number:
PCT/US2000/014205
Publication Date:
August 09, 2001
Filing Date:
May 24, 2000
Export Citation:
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Assignee:
COR THERAPEUTICS INC (US)
International Classes:
C07D213/74; A61K31/18; A61K31/198; A61K31/341; A61K31/397; A61K31/40; A61K31/401; A61K31/4164; A61K31/44; A61K31/4406; A61K31/4427; A61K31/4453; A61K31/472; A61K31/4725; A61K31/495; A61K31/496; A61K31/5375; A61K31/55; A61P7/02; A61P9/00; A61P9/10; A61P43/00; C07C311/16; C07C311/21; C07C311/46; C07D205/04; C07D207/16; C07D207/20; C07D207/325; C07D213/40; C07D213/64; C07D213/72; C07D213/75; C07D213/82; C07D217/22; C07D231/12; C07D233/68; C07D295/18; C07D295/192; C07D295/22; C07D295/26; C07D307/38; C07D307/52; C07D401/12; (IPC1-7): C07C311/46; A61K31/18; A61K31/277; A61K31/501; A61P7/02; C07D213/74
Domestic Patent References:
WO1998057934A11998-12-23
WO1998028282A21998-07-02
WO1998028269A11998-07-02
Foreign References:
US3235597A1966-02-15
DE1062253B1959-07-30
US3895010A1975-07-15
Other References:
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