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Title:
INHIBITORS OF beta-SECRETASE, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF ALZHEIMER'S DISEASE OR MILD COGNITIVE IMPAIRMENT
Document Type and Number:
WIPO Patent Application WO2004041211
Kind Code:
A3
Abstract:
One aspect of the present invention relates to urea-containing compounds. In certain embodiments, the urea-containing compounds of the present invention comprise a heteroaromatic moiety. Another aspect of the present invention relates to a method of inhibiting a beta-secretase using a urea-containing compound of the present invention. A third aspect of the present invention relates to a method of treating Alzheimer's Disease or mild cognitive impairment using a urea-containing compound of the present invention.

Inventors:
KOZIKOWSKI ALAN P (US)
AISEN PAUL S (US)
PETUKHOV PAVEL (US)
Application Number:
US0335219W
Publication Date:
September 10, 2004
Filing Date:
November 03, 2003
Export Citation:
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Assignee:
UNIV GEORGETOWN (US)
KOZIKOWSKI ALAN P (US)
AISEN PAUL S (US)
PETUKHOV PAVEL (US)
International Classes:
A61K31/34; A61K31/38; A61K31/40; C07C233/00; C07C275/14; C07C275/16; C07C275/20; C07C275/24; C07D207/10; C07D307/02; C07D307/66; C07D333/36; C07D405/00; A61K; (IPC1-7): A61K31/34; A61K31/38; A61K31/40; C07C233/00; C07D207/10; C07D307/02; C07D333/36; C07D405/00
Foreign References:
US6531610B12003-03-11
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