Title:
IMIDAZO BENZAMIDE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2016/138631
Kind Code:
A1
Abstract:
Compounds of formula I and the pharmaceutically acceptable salt thereof are disclosed, wherein R is selected from the group consisting of O and NH, R 1 is selected from the group consisting of CF 3, OCF 3 and Cl.
Inventors:
MA TIANWEI (US)
ZHANG HAIZHEN (US)
ZHOU JINGYE (US)
ZHANG HAIZHEN (US)
ZHOU JINGYE (US)
Application Number:
PCT/CN2015/073563
Publication Date:
September 09, 2016
Filing Date:
March 03, 2015
Export Citation:
Assignee:
LILLY CO ELI (US)
LILLY CHINA RES AND DEV CO LTD (CN)
LILLY CHINA RES AND DEV CO LTD (CN)
International Classes:
C07D405/14; A61K31/4196; A61K31/4245; A61P3/10; A61P5/48; A61P5/50; C07D233/02; C07D249/08; C07D309/02
Foreign References:
| US20120004227A1 | 2012-01-05 |
Other References:
LIZARZABURU, MIKE ET AL.: "Discovery and optimization of a novel series of GPR142 agonists for the treatment of type 2 diabetes mellitus", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, vol. 22, 23 July 2012 (2012-07-23), ISSN: 0960-894X
TODA, NARIHIRO ET AL.: "Potent and Orally Bioavailable GPR142 Agonists as Novel Insulin Secretagogues for the Treatment of Type 2 Diabetes", ACS MEDICINAL CHEMISTRY LETTERS, vol. 4, 17 June 2013 (2013-06-17), pages 790 - 794, XP055219528, ISSN: 1948-5875, DOI: doi:10.1021/ml400186z
TODA, NARIHIRO ET AL.: "Potent and Orally Bioavailable GPR142 Agonists as Novel Insulin Secretagogues for the Treatment of Type 2 Diabetes", ACS MEDICINAL CHEMISTRY LETTERS, vol. 4, 17 June 2013 (2013-06-17), pages 790 - 794, XP055219528, ISSN: 1948-5875, DOI: doi:10.1021/ml400186z
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
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