Title:
IMIDAZOLIDINONE COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/088845
Kind Code:
A1
Abstract:
An imidazolidinone compound as represented by formula (I) or a stereoisomer, a geometric isomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing the compound, a synthetic method, and application thereof.
Inventors:
ZU HOUXIAN (CN)
SONG XIZHEN (CN)
CHEN KAI (CN)
LIU XIANGYONG (CN)
CHEN JIE (CN)
BIAN YAJING (CN)
DING LIEMING (CN)
WANG JIABING (CN)
SONG XIZHEN (CN)
CHEN KAI (CN)
LIU XIANGYONG (CN)
CHEN JIE (CN)
BIAN YAJING (CN)
DING LIEMING (CN)
WANG JIABING (CN)
Application Number:
PCT/CN2020/126372
Publication Date:
May 14, 2021
Filing Date:
November 04, 2020
Export Citation:
Assignee:
BETTA PHARMACEUTICALS CO LTD (CN)
International Classes:
C07D498/04; A61K31/4188; A61K31/553; A61P35/00; C07D498/14
Domestic Patent References:
| WO2019228341A1 | 2019-12-05 | |||
| WO2017001645A1 | 2017-01-05 | |||
| WO2017001658A1 | 2017-01-05 | |||
| WO2012126901A1 | 2012-09-27 | |||
| WO2011036280A1 | 2011-03-31 |
Other References:
HAN, C. ET AL.: "Synthesis of PI3K Inhibitor GDC-0077 via a Stereocontrolled N-Arylation of α-Amino Acids.", TETRAHEDRON, vol. 75, 27 April 2019 (2019-04-27), XP085743440, DOI: 10.1016/j.tet.2019.04.057
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