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Title:
IMMORTALIZED PORCINE ALVEOLAR MACROPHAGE CULTURED CELL LINE, METHOD FOR PRODUCING IMMORTALIZED PORCINE ALVEOLAR MACROPHAGE CULTURED CELL LINE, REAGENT FOR PREPARING IMMORTALIZED PORCINE ALVEOLAR MACROPHAGE CULTURED CELL LINE, AND METHOD FOR PRODUCING VACCINE
Document Type and Number:
WIPO Patent Application WO/2022/019306
Kind Code:
A1
Abstract:
This immortalized porcine alveolar macrophage cultured cell line has a viral long terminal repeat, expresses a gene that induces cell immortalization, and is sensitive to porcine reproductive and respiratory syndrome virus and/or African swine fever virus.

Inventors:
OZAWA MAKOTO (JP)
SUGAYA YUIKO (JP)
Application Number:
PCT/JP2021/027164
Publication Date:
January 27, 2022
Filing Date:
July 20, 2021
Export Citation:
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Assignee:
UNIV KAGOSHIMA (JP)
International Classes:
C12N5/10; C12N5/02; C12N5/0786; C12N15/37
Foreign References:
JP2017500029A2017-01-05
CN109517797A2019-03-26
Other References:
WANG TONG-YUN, LIU YONG-GANG, LI LIANG, WANG GANG, WANG HAI-MING, ZHANG HONG-LIANG, ZHAO SHI-FEI, GAO JIA-CONG, AN TONG-QING, TIAN: "Porcine alveolar macrophage CD163 abundance is a pivotal switch for porcine reproductive and respiratory syndrome virus infection", ONCOTARGET, IMPACT JOURNALS LLC, UNITED STATES, vol. 9, no. 15, 23 February 2018 (2018-02-23), United States , pages 12174 - 12185, XP055899617, ISSN: 1949-2553, DOI: 10.18632/oncotarget.24040
WEINGARTL H M; SABARA M; PASICK J; VAN MOORLEHEM E; BABIUK L: "Continuous porcine cell lines developed from alveolar macrophages: Partial characterization and virus susceptibility", JOURNAL OF VIROLOGICAL METHODS, ELSEVIER BV, NL, vol. 104, no. 2, 1 July 2002 (2002-07-01), NL , pages 203 - 216, XP002604365, ISSN: 0166-0934, DOI: 10.1016/S0166-0934(02)00085-X
Attorney, Agent or Firm:
KIMURA Mitsuru (JP)
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