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Patent Searching and Data


Title:
IMMUNONEUTRAL SILK-FIBER-BASED MEDICAL DEVICES
Document Type and Number:
WIPO Patent Application WO2004080346
Kind Code:
A9
Abstract:
Silk is purified to eliminate immunogenic components (particularly sericin) and is used to form tissue-supporting prosthetic devices for implantation. The fabrics can carry functional groups, drugs, and other biological reagents. Applications include hernia repair, tissue wall reconstruction, and organ support, such as bladder slings. The silk fibers are arranged in parallel and, optionally, intertwined (e.g., twisted) to form a construct; sericin may be extracted at any point during the formation of the fabric, leaving a construct of silk fibroin fibers having excellent tensile strength and other mechanical properties.

Inventors:
ALTMAN GREGORY H (US)
HORAN DAVID J (US)
CHEN JINGSONG (US)
HORAN REBECCA L (US)
Application Number:
PCT/US2004/007647
Publication Date:
February 17, 2005
Filing Date:
March 11, 2004
Export Citation:
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Assignee:
TISSUE REGENERATION INC (US)
ALTMAN GREGORY H (US)
UNIV TUFTS (US)
HORAN DAVID J (US)
CHEN JINGSONG (US)
HORAN REBECCA L (US)
International Classes:
D04B1/14; D04B21/16; D04H1/42; D06L1/12; A61F; (IPC1-7): D04B1/14; D06L1/12
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