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Title:
IMPATIENS BALSAMINA-DERIVED ANTI-BACTERIAL PEPTIDE AND ANTI-BACTERIAL COMPOSITION CONTAINING SAME
Document Type and Number:
WIPO Patent Application WO/2023/027240
Kind Code:
A1
Abstract:
The present invention relates to an Impatiens balsamina-derived anti-bacterial peptide and an anti-bacterial composition comprising same. Specifically, six types of peptide derivatives were prepared on the basis of the sequence of a conventional Impatiens balsamina-derived peptide Ib-AMP4 known to have anti-fungal activity, and a peptide derivative exhibiting anti-bacterial and anti-fungal activity better than that of Ib-AMP4 and having weak cytotoxicity and hemolytic properties has been identified, and thus the peptide derivative, which is an Impatiens balsamina-derived anti-bacterial peptide, can be used, in the fields of medicine, cosmetics and food, as an anti-bacterial or anti-fungal pharmaceutical composition, antibiotic, food preservative, cosmetic preservative, pharmaceutical preservative or feed additive preservative, and the like.

Inventors:
CHA SANG DO (KR)
CHO MIN SEOK (KR)
CHOI WON SEOK (KR)
CHO JANG HEE (KR)
YU JI WON (KR)
Application Number:
PCT/KR2021/014309
Publication Date:
March 02, 2023
Filing Date:
October 15, 2021
Export Citation:
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Assignee:
V&CO CO LTD (KR)
International Classes:
C07K7/06; A23K20/147; A23L3/34; A61K8/64; A61K36/185; A61K38/08; A61K47/42; A61P31/10; A61Q19/00; C07K14/415
Foreign References:
US5861480A1999-01-19
KR20170025799A2017-03-08
KR20180051474A2018-05-16
Other References:
THEVISSEN, K. FRANCOIS, I.E.J.A. SIJTSMA, L. AMERONGEN, A.V. SCHAAPER, W.M.M. MELOEN, R. POSTHUMA-TRUMPIE, T. BROEKA: "Antifungal activity of synthetic peptides derived from Impatiens balsamina antimicrobial peptides Ib-AMP1 and Ib-AMP4", PEPTIDES, ELSEVIER, AMSTERDAM, NL, vol. 26, no. 7, 1 July 2005 (2005-07-01), AMSTERDAM, NL , pages 1113 - 1119, XP004931281, ISSN: 0196-9781, DOI: 10.1016/j.peptides.2005.01.008
PRADA-PRADA SERGIO, FLÓREZ-CASTILLO JOHANNA, FARFÁN-GARCÍA ANA, GUZMÁN FANNY, HERNÁNDEZ-PEÑARANDA INDIRA: "Antimicrobial activity of Ib-M peptides against Escherichia coli O157: H7", PLOS ONE, vol. 15, no. 2, 13 February 2020 (2020-02-13), pages e0229019, XP093038939, DOI: 10.1371/journal.pone.0229019
Attorney, Agent or Firm:
TEHERAN PATENT FIRM (KR)
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