Title:
IMPROVED MUCOSAL DELIVERY OF VITAMIN B12
Document Type and Number:
WIPO Patent Application WO/2016/199165
Kind Code:
A3
Abstract:
This invention comprises a method of transmucosal delivery of process of Vitamin B 12 without the need of intrinsic factor comprising administering a solid composition comprising a Vitamin B 12 and at least one bifunctional macromolecule with hydrophilic exterior and with hydrophobic pockets capable of pocketing Vitamin B12 material,, illustrated by cyclodextrin, at least one permeation enhancer, illustrated by Isopropyl Myristate and at least one agent that is mucoadhessive as well as penetration enhancer, illustrated by chitosan. The solid composition of Vitamin B 12 of claim 2 may comprise a lozenge, a candy, a wafer, a tablet, a patch, a film, a spray, a lip balm, or gum.
Inventors:
DAUD ANWAR (IN)
SAPKAL NIDHI (IN)
DAUD LUBNA (IN)
BONDE MINAL (IN)
SAPKAL NIDHI (IN)
DAUD LUBNA (IN)
BONDE MINAL (IN)
Application Number:
PCT/IN2016/050168
Publication Date:
February 09, 2017
Filing Date:
June 04, 2016
Export Citation:
Assignee:
ZIM LABORATORIES LTD (IN)
International Classes:
C07H23/00
Domestic Patent References:
| WO2014152504A1 | 2014-09-25 | |||
| WO2008113483A2 | 2008-09-25 | |||
| WO2007085888A1 | 2007-08-02 |
Foreign References:
| US6255294B1 | 2001-07-03 |
Attorney, Agent or Firm:
SAVANGIKAR, Vasant Anantrao (IN)
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