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Patent Searching and Data


Title:
IMPROVED SYNTHESIS OF CAPURAMYCIN AND ITS ANALOGUES
Document Type and Number:
WIPO Patent Application WO/2015/027137
Kind Code:
A8
Abstract:
Provided herein are compounds of Formula I, Formula II, and Formula X, which are useful for the treatment of infectious diseases. Also provided herein are processes for preparing 1-[5-0-[4,6-Dideoxy-6-oxo-6-[[[(3S)-hexahydro-2-oxo-1H-azepine]-3-y1]amino]-Pβ-L-erythro-4- hexenopyranosyl]-3-0-methyl 6-deoxy-6-amino-α-L-talofuranuronosyl]-1,2,3,4-tetrahydro-2,4- dioxopyrimidine (capuramycin), analogues thereof, and intermediates useful therefore. Also provided herein are III, IIIa, and IX, which are useful in the process for preparing capuramycin and/or a certain compound of Formula I.

Inventors:
KUROSU MICHIO (US)
Application Number:
PCT/US2014/052246
Publication Date:
December 23, 2015
Filing Date:
August 22, 2014
Export Citation:
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Assignee:
UNIV TENNESSEE RES FOUNDATION (US)
International Classes:
C07H19/06; A61K31/7042; A61P31/04; C07H19/067
Attorney, Agent or Firm:
TRINQUE, Brian, C. et al. (28 State StretBoston, MA, US)
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