Title:
INOTODIOL ESTER DERIVATIVE PRECURSOR DRUG
Document Type and Number:
WIPO Patent Application WO/2022/031130
Kind Code:
A1
Abstract:
The present invention relates to an ester derivative precursor drug of inotodiol and a use thereof. The precursor drug has an increased solubility in an inorganic solvent and an organic solvent and an improved stability and as such, can be used for the treatment of inflammatory diseases or various inflammations including allergic diseases.
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Inventors:
PARK JONGTAE (KR)
NGUYEN PHU CUONG (KR)
PARK KYUBEEN (KR)
LEE NAN YOUNG (KR)
NGUYEN PHU CUONG (KR)
PARK KYUBEEN (KR)
LEE NAN YOUNG (KR)
Application Number:
PCT/KR2021/010448
Publication Date:
February 10, 2022
Filing Date:
August 06, 2021
Export Citation:
Assignee:
CARBOEXPERT INC (KR)
IAC IN NAT UNIV CHUNGNAM (KR)
IAC IN NAT UNIV CHUNGNAM (KR)
International Classes:
C07J63/00; A61K31/575; A61P37/08
Foreign References:
| KR101893754B1 | 2018-08-31 | |||
| CN108517001A | 2018-09-11 |
Other References:
MA LISHUAI, HAIXIA CHEN, PENG DONG, XUEMING LU: "Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus", FOOD CHEMISTRY, vol. 139, 15 August 2013 (2013-08-15), pages 503 - 508, XP055895131, DOI: 10.1016/j.foodchem.2013.01.030
HASEGAWA HIDEO, IKUO SAIKI: "Oleoyl triterpene glycoside biotransformed from ginseng suppresses growth and metastasis of murine B16-F10 melanoma via immunostimulation", JOURNAL OF TRADITIONAL MEDICINES, vol. 17, 31 December 2000 (2000-12-31), pages 186 - 193, XP055895135
FERRIZ J.M., VINSOVA J.: "Prodrug Design of Phenolic Drugs", CURRENT PHARMACEUTICAL DESIGN, BENTHAM SCIENCE PUBLISHERS, NL, vol. 16, no. 18, 1 June 2010 (2010-06-01), NL , pages 2033 - 2052, XP055834786, ISSN: 1381-6128, DOI: 10.2174/138161210791293042
See also references of EP 4194463A4
HASEGAWA HIDEO, IKUO SAIKI: "Oleoyl triterpene glycoside biotransformed from ginseng suppresses growth and metastasis of murine B16-F10 melanoma via immunostimulation", JOURNAL OF TRADITIONAL MEDICINES, vol. 17, 31 December 2000 (2000-12-31), pages 186 - 193, XP055895135
FERRIZ J.M., VINSOVA J.: "Prodrug Design of Phenolic Drugs", CURRENT PHARMACEUTICAL DESIGN, BENTHAM SCIENCE PUBLISHERS, NL, vol. 16, no. 18, 1 June 2010 (2010-06-01), NL , pages 2033 - 2052, XP055834786, ISSN: 1381-6128, DOI: 10.2174/138161210791293042
See also references of EP 4194463A4
Attorney, Agent or Firm:
THEWAVE IP LAW FIRM (KR)
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