Title:
INTERMEDIATE OF REMDESIVIR AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2021/175296
Kind Code:
A1
Abstract:
The present invention provides an intermediate of Remdesivir and a preparation method therefor. The preparation method has the advantages of low costs, high yield, good product purity, etc. , and can achieve the efficient synthesis of Remdesivir. In each formula, R1, R2, R3, R4, R5, R8, PG and X are as defined in the description.
Inventors:
XIE YUANCHAO (CN)
HU TIANWEN (CN)
ZHU FUQIANG (CN)
TIAN GUANGHUI (CN)
SHEN JINGSHAN (CN)
HU TIANWEN (CN)
ZHU FUQIANG (CN)
TIAN GUANGHUI (CN)
SHEN JINGSHAN (CN)
Application Number:
PCT/CN2021/079143
Publication Date:
September 10, 2021
Filing Date:
March 04, 2021
Export Citation:
Assignee:
SHANGHAI INST MATERIA MEDICA CAS (CN)
TOPHARMAN SHANGHAI CO LTD (CN)
VIGONVITA LIFE SCIENCES CO LTD (CN)
TOPHARMAN SHANGHAI CO LTD (CN)
VIGONVITA LIFE SCIENCES CO LTD (CN)
International Classes:
C07H7/06
Domestic Patent References:
| WO2012012776A1 | 2012-01-26 | |||
| WO2016069826A1 | 2016-05-06 |
Foreign References:
| CN111440176A | 2020-07-24 |
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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