ISLET CELLS FROM HUMAN EMBRYONIC STEM CELLS

Title:

ISLET CELLS FROM HUMAN EMBRYONIC STEM CELLS

Document Type and Number:

WIPO Patent Application WO2003050249

Kind Code:

B1

Abstract:

This disclosure provides a system for producing pancreatic islet cells from embryonic stem cells. Differentiation is initiated towards endoderm cells, and focused using reagents that promote emergence of islet precursors and mature insulin-secreting cells. High quality populations of islet cells can be produced in commercial quantities for use in research, drug screening, or regenerative medicine.

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Inventors:

FISK GREGORY J (US)
INOKUMA MARGARET S (US)

Application Number:

PCT/US2002/039089

Publication Date:

May 21, 2004

Filing Date:

December 06, 2002

Export Citation:

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Assignee:

GERON CORP (US)
FISK GREGORY J (US)
INOKUMA MARGARET S (US)

International Classes:

A01N63/00; A01N65/00; A61K48/00; C12M3/00; C12N5/00; C12N5/02; C12N5/071; C12N5/074; C12N15/17; C12N15/18; C12N15/85; A61K35/12; (IPC1-7): C12N5/00; C12N5/02; C12N5/06; A01N63/00; A01N65/00; A61K48/00

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