Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
ISOLATION AND STRUCTURAL ELUCIDATION OF THE HUMAN CANCER CELL GROWTH INHIBITORY COMPOUND DENOMINATED "AGELAGALASTATIN"
Document Type and Number:
WIPO Patent Application WO1999063942
Kind Code:
A3
Abstract:
A human cancer cell line bioassay-directed investigation of the Western Pacific marine sponge agelas sp. led to isolation of a trace (7.42 x 10<-6> % yield) cancer cell growth inhibitor (lung NCI-H460 GI50 0.77 mu g/ml to ovary OVCAR-3 GI50 2.8 mu g/ml) designated agelagalastatin (6). Agelagalastatin is the first example of a natural product containing a digalactofuranosyl unit.

Inventors:
PETTIT GEORGE R (US)
XU JUN-PING (US)
Application Number:
PCT/US1999/012935
Publication Date:
February 03, 2000
Filing Date:
June 09, 1999
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
UNIV ARIZONA STATE (US)
PETTIT GEORGE R (US)
XU JUN PING (US)
International Classes:
A61K31/7028; A61P35/00; C07H15/04; (IPC1-7): A01N43/04; C07H15/00
Foreign References:
US5936076A1999-08-10
Download PDF: