Title:
KERATIN BD-14, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/083204
Kind Code:
A1
Abstract:
Provided are keratin BD-14, a nucleic acid molecule encoding keratin BD-14, an expression vector containing the nucleic acid molecule, a host cell containing the expression vector or a genome integrated with the nucleic acid molecule, a preparation method for keratin BD-14, a pharmaceutical composition containing keratin BD-14, and an application of said keratin BD-14, nucleic acid molecule, expression vector, host cell, or pharmaceutical composition in preparing antipyretic and analgesic, antitussive and expectorant, anticonvulsant, antiepileptic, blood pressure lowering, anti-inflammatory and antiviral drugs.
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Inventors:
YU SHISHAN (CN)
WANG XIAOLIANG (CN)
LIU YUNBAO (CN)
SU GUOZHU (CN)
LI MI (CN)
XU SHAOFENG (CN)
ZHANG MI (CN)
CAI JIE (CN)
WANG XIAOLIANG (CN)
LIU YUNBAO (CN)
SU GUOZHU (CN)
LI MI (CN)
XU SHAOFENG (CN)
ZHANG MI (CN)
CAI JIE (CN)
Application Number:
PCT/CN2020/124365
Publication Date:
May 06, 2021
Filing Date:
October 28, 2020
Export Citation:
Assignee:
INST OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCICENCES (CN)
International Classes:
C07K14/47; A61K38/17; A61P9/12; A61P11/00; A61P25/08; A61P29/00; A61P31/12; C12N15/12; C12N15/63
Foreign References:
| CN108434064A | 2018-08-24 | |||
| CN102993291A | 2013-03-27 |
Other References:
DATABASE Protein Genpept; ANONYMOUS: "RecName: Full=Keratin, type II cytoskeletal 8; AltName: Full=Cytokeratin-8; Short=CK-8; AltName: Full=Cytokeratin-A; AltName: Full=Keratin-8; Short=K8; AltName: Full=Type-II keratin Kb8", XP055817356, retrieved from NCBI Database accession no. P05786.3
伍红星 等 (WU, HONGXING ET AL.): "羚羊角煎剂对持续发热患儿血清TNF-α, IL-6的影响 (Non-official translation: Effect of Antelope Horn Decoction on Serum TNF-α and IL-6 in Children with Persistent Fever)", CHINESE JOURNAL OF ETHNOMEDICINE AND ETHNOPHARMACY, vol. 27, no. 14, 31 July 2018 (2018-07-31)
伍红星 等 (WU, HONGXING ET AL.): "羚羊角煎剂对持续发热患儿血清TNF-α, IL-6的影响 (Non-official translation: Effect of Antelope Horn Decoction on Serum TNF-α and IL-6 in Children with Persistent Fever)", CHINESE JOURNAL OF ETHNOMEDICINE AND ETHNOPHARMACY, vol. 27, no. 14, 31 July 2018 (2018-07-31)
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