Title:
KERATIN BD-5, PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/083198
Kind Code:
A1
Abstract:
Provided are keratin BD-5, an encoding nucleic acid molecule thereof, an expression vector, a host cell, and a pharmaceutical composition containing the keratin. The keratin BD-5 can be used for preparing drugs having antipyretic and analgesic, antitussive and expectorant, and antiepileptic effects.
Inventors:
YU SHISHAN (CN)
WANG XIAOLIANG (CN)
SHI GUORU (CN)
FU JIANG (CN)
SU GUOZHU (CN)
WANG LING (CN)
LI JIANG (CN)
XU SHAOFENG (CN)
LI YONG (CN)
WANG XIAOLIANG (CN)
SHI GUORU (CN)
FU JIANG (CN)
SU GUOZHU (CN)
WANG LING (CN)
LI JIANG (CN)
XU SHAOFENG (CN)
LI YONG (CN)
Application Number:
PCT/CN2020/124345
Publication Date:
May 06, 2021
Filing Date:
October 28, 2020
Export Citation:
Assignee:
INST OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCICENCES (CN)
International Classes:
C07K14/47; A61K38/17; A61P11/00; A61P25/08; A61P29/00; C12N15/12; C12N15/63
Foreign References:
CN109078023A | 2018-12-25 | |||
CN1324859A | 2001-12-05 | |||
CN102993291A | 2013-03-27 | |||
US5994081A | 1999-11-30 |
Other References:
DATABASE Nucleotide GenBank; ANONYMOUS: "Bos taurus keratin 32, mRNA (cDNA clone MGC:155138 IMAGE:8232357)", XP055817352, retrieved from NCBI
WU HONGXING, CHEN JINGGUO , LI ZHENHUA: "Effect of Antelope Horn Decoction on Serum TNF-α and IL-6 in Children with Persistent Fever", CHINESE JOURNAL OF ETHNOMEDICINE AND ETHNOPHARMACY, vol. 27, no. 14, 31 July 2018 (2018-07-31), pages 79 - 80, XP055806911, ISSN: 1007-8517
ZHANG LONGFEI , HU JINGHONG , ZHANG YONGQING: "Research overview of the pharmacological action of Cornu Saigae Tataricae", CHINA MEDICAL HERALD, CN, vol. 10, no. 28, 5 October 2013 (2013-10-05), CN, pages 23 - 26+33, XP055806914, ISSN: 1673-7210
WU HONGXING, CHEN JINGGUO , LI ZHENHUA: "Effect of Antelope Horn Decoction on Serum TNF-α and IL-6 in Children with Persistent Fever", CHINESE JOURNAL OF ETHNOMEDICINE AND ETHNOPHARMACY, vol. 27, no. 14, 31 July 2018 (2018-07-31), pages 79 - 80, XP055806911, ISSN: 1007-8517
ZHANG LONGFEI , HU JINGHONG , ZHANG YONGQING: "Research overview of the pharmacological action of Cornu Saigae Tataricae", CHINA MEDICAL HERALD, CN, vol. 10, no. 28, 5 October 2013 (2013-10-05), CN, pages 23 - 26+33, XP055806914, ISSN: 1673-7210
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