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Title:
KEY INTERMEDIATE FOR SYNTHESIZING PROSTAGLANDIN COMPOUNDS AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/057734
Kind Code:
A1
Abstract:
The present invention relates to the technical field of organic chemical engineering, and in particular to a key intermediate for synthesizing prostaglandin compounds and a preparation method therefor. When applied to the synthesis of prostaglandin compounds, the process flow is simplified, the yield and product purity are improved, the production costs are reduced, and the industrial application is easy.

Inventors:
DING XIAOBING (CN)
LANG QIWEI (CN)
SU WEI (CN)
GAO SHUANG (CN)
Application Number:
PCT/CN2021/117634
Publication Date:
March 24, 2022
Filing Date:
September 10, 2021
Export Citation:
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Assignee:
SHENZHEN CATALYS TECH CO LTD (CN)
International Classes:
C07C405/00; C07D307/93; C07D307/937; C07D311/94; C07D317/06; C07D317/20; C07D317/26; C07D493/08; C07F7/18
Foreign References:
US5599837A1997-02-04
Other References:
ZHANG FUHAO; ZENG JINGWEN; GAO MOHAN; WANG LINZHOU; CHEN GEN-QIANG; LU YIXIN; ZHANG XUMU: "Concise, scalable and enantioselective total synthesis of prostaglandins", NATURE CHEMISTRY, NATURE PUBLISHING GROUP UK, LONDON, vol. 13, no. 7, 27 May 2021 (2021-05-27), London, pages 692 - 697, XP037495041, ISSN: 1755-4330, DOI: 10.1038/s41557-021-00706-1
TAEHYEONG KIM ET AL.: "Total synthesis of PGF2α and 6, 15-diketo-PGF1α and formal synthesis of 6-keto-PGF1α via three-component coupling", TETRAHEDRON, vol. 75, no. 42, 10 September 2019 (2019-09-10), XP085841434, ISSN: 0040-4020, DOI: 10.1016/j.tet.2019.130593
"STEREOSPECIFIC TOTAL SYNTHESIS OF THE NATURAL AND RACEMIC PROSTAGLANDINS OF THE E AND F SERIES", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, vol. 94, no. 12, 14 June 1972 (1972-06-14), pages 4342/4343, XP000960050, ISSN: 0002-7863, DOI: 10.1021/ja00767a052
Attorney, Agent or Firm:
SHENZHEN LANFENG SHENGSHI INTELLECTUAL PROPERTY AGENCY CO., LTD (CN)
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