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Title:
LIPOTEICHOIC ACID-DERIVED GLYCOLIPIDS, AND COMPOSITIONS COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2011/025286
Kind Code:
A3
Abstract:
The present invention relates to lipoteichoic acid-derived glycolipids, and to pharmaceutical, food or cosmetic compositions and vaccine adjuvants comprising same. The lipoteichoic acid-derived glycolipids according to the present invention inhibit the production of inflammatory cytokines and thus have anti-inflammatory effects. Therefore, pharmaceutical, food or cosmetic compositions comprising lipoteichoic acid-derived glycolipids of the present invention can be employed for the purpose of preventing and treating inflammatory diseases. The lipoteichoic acid-derived glycolipids of the present invention can be also used as vaccine adjuvants.

Inventors:
CHUNG DAE KYUN (KR)
JANG KYOUNG SOON (KR)
KIM BYUNG GEE (KR)
KIM HAN GEUN (KR)
KIM NA RA (KR)
LEE HEA YOUNG (KR)
JUNG BONG JUN (KR)
KIM TAE RAHK (KR)
JEONG JI HYE (KR)
Application Number:
PCT/KR2010/005755
Publication Date:
July 14, 2011
Filing Date:
August 26, 2010
Export Citation:
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Assignee:
RNA INC (KR)
CHUNG DAE KYUN (KR)
JANG KYOUNG SOON (KR)
KIM BYUNG GEE (KR)
KIM HAN GEUN (KR)
KIM NA RA (KR)
LEE HEA YOUNG (KR)
JUNG BONG JUN (KR)
KIM TAE RAHK (KR)
JEONG JI HYE (KR)
International Classes:
C07H1/06; C07H11/04; C07H15/04
Foreign References:
KR20070078107A2007-07-31
US20040137554A12004-07-15
Other References:
MORATH, S. ET AL.: "Structure-Function Relationship of Cytokine Induction by Lipoteichoic Acid from Staphylococcus aureus", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 193, 5 February 2001 (2001-02-05), pages 393 - 397, XP008154433
FISCHER, W.: "Lipoteichoic acid and lipids in the membrane of Staphylococcus aureus", MEDICAL MICROBIOLOGY AND IMMUNOLOGY, vol. 183, May 1994 (1994-05-01), pages 61 - 76, XP008154435
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (BYC Bldg. 648-1,Yeoksam-dong, Gangnam-gu, Seoul 135-080, KR)
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Claims: