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Title:
LUMEN TISSUE CONSTRUCT PRINTING DEVICE, 3D BIOPRINTER AND PRINTING METHOD
Document Type and Number:
WIPO Patent Application WO/2022/143229
Kind Code:
A1
Abstract:
The present application relates to a lumen tissue construct printing device, a 3D bioprinter and a printing method. The lumen tissue construct printing device comprises a hollow rod assembly, an adhesive coating assembly, a spray head assembly and a bioprinting assembly. The bioprinting assembly receives bioink sprayed by the spray head assembly and forms a bio-construct. A lumen tissue is fixed inside the hollow rod assembly, and a medical adhesive is arranged on an inner surface of the lumen tissue by means of the adhesive coating assembly. The bio-construct is then applied onto the inner surface of the lumen tissue by means of the bioprinting assembly. The medical adhesive is arranged on the inner surface of the lumen tissue and then comes into contact with the bio-construct, which prevents the problem of the adhesion between the medical adhesive and an artificial blood vessel not being firm enough due to a polymerization reaction between the medical adhesive and hydroxide anions in water in the bioink. In addition, the medical adhesive is arranged on the inner surface of the lumen tissue and has a uniform thickness, which solves the problem of toxicity to cells in the bioink caused by excessive use of the medical adhesive due to excessively thick medical adhesive in a local part.

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Inventors:
XU ZIQING (CN)
HE JUNXUAN (CN)
LI YIJUN (CN)
XIANG JIE (CN)
JIANG ZHI (CN)
Application Number:
PCT/CN2021/139249
Publication Date:
July 07, 2022
Filing Date:
December 17, 2021
Export Citation:
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Assignee:
REVOTEK CO LTD (CN)
International Classes:
B29C64/20; A61F2/06; B29C64/112; B29C69/00; B33Y30/00
Foreign References:
CN110053255A2019-07-26
CN107456296A2017-12-12
CN111645332A2020-09-11
CN110614765A2019-12-27
US6776604B12004-08-17
US20100330144A12010-12-30
CN105919649A2016-09-07
Attorney, Agent or Firm:
BEIJING EAST IP LTD. (CN)
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