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Title:
MACROLIDE DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2013/008928
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a novel compound useful for the prevention or treatment of diseases such as cancerous angiogenesis, chronic rheumatoid arthritis, intimal hyperplasia, vascular atherosclerosis, hemorrhagic stroke, acute myocardial infarction, chronic heart failure, aneurysm, cancer metastasis, adult respiratory distress syndrome, asthma, idiopathic pulmonary fibrosis, chronic sinusitis, bronchitis or chronic obstructive pulmonary disease, or a pharmaceutically acceptable salt thereof. The present invention provides a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.

Inventors:
KASHIMURA MASATO (JP)
OGITA HARUHISA (JP)
KAWAMURA MADOKA (JP)
TANIKAWA TETSUYA (JP)
KUBO TAKEKAZU (JP)
ASANO YASUO (JP)
Application Number:
PCT/JP2012/067987
Publication Date:
January 17, 2013
Filing Date:
July 13, 2012
Export Citation:
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Assignee:
TAISHO PHARMACEUTICAL CO LTD (JP)
KASHIMURA MASATO (JP)
OGITA HARUHISA (JP)
KAWAMURA MADOKA (JP)
TANIKAWA TETSUYA (JP)
KUBO TAKEKAZU (JP)
ASANO YASUO (JP)
International Classes:
C07H17/08; A61K31/7048; A61P9/00; A61P9/04; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P11/16; A61P19/02; A61P29/00; A61P35/00; A61P35/04; A61P43/00
Domestic Patent References:
WO2007129646A12007-11-15
Foreign References:
JPS55151598A1980-11-26
Other References:
MORIMOTO S ET AL.: "Chemical modification of erythromycins. VII. Molecular rearrangement observed during chemical modification study of the desosamine unit of erythromycins", HETEROCYCLES, vol. 31, no. 2, 1990, pages 305 - 319
Attorney, Agent or Firm:
INABA, Yoshiyuki et al. (JP)
Yoshiyuki Inaba (JP)
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Claims: