Title:
MACROMOLECULAR PRODRUGS FOR LIGHT-EMITTING DIODES AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/146553
Kind Code:
A8
Abstract:
Provided herein are compositions comprising macromolecular photocleavable prodrug compounds of Formula (I), and pharmaceutically acceptable salts, co-crystals, tautomers, stereoisomers, solvates, hydrates, polymorphs, and isotopically enriched derivatives thereof. Also provided are methods, uses, pharmaceutical compositions, and kits involving the inventive compounds or compositions for treating and/or preventing a disease and/or condition (e.g., inflammatory disease, infectious disease, pain) in a subject, optionally comprising illumination of the compound, composition, or pharmaceutical composition with light of an absorption wavelength sufficient to cleave the bonds between each instance of L and each instance of X upon illumination with the light (e.g., light between approximately 200 nm to 500 nm).
Inventors:
KOHANE DANIEL (US)
ZHANG WEI (US)
ZHANG WEI (US)
Application Number:
PCT/US2021/013628
Publication Date:
September 10, 2021
Filing Date:
January 15, 2021
Export Citation:
Assignee:
CHILDRENS MEDICAL CENTER (US)
International Classes:
A61K47/50; A61K47/58; C08F20/56
Attorney, Agent or Firm:
CHAO, Jessica, J. et al. (US)
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