Title:
MASS MANUFACTURING APPARATUS OF POLYMER MICRO-SCAFFOLD AND MASS MANUFACTURING METHOD USING SAME
Document Type and Number:
WIPO Patent Application WO/2021/060622
Kind Code:
A1
Abstract:
The present invention relates to a manufacturing apparatus capable of manufacturing stable and uniform particles, and manufacturing micro-scaffolds in large quantities for a long time, the manufacturing apparatus comprising: a first solution storage unit for storing a polymer support structure solution; a second solution storage unit for storing an emulsifier solution; a gas storage unit connected to each of the first solution storage unit and the second solution storage unit and providing a transport gas for transporting the support structure solution and the emulsifier solution; a pressurization unit for providing pressure to the transport gas provided to the first solution storage unit and the second solution storage unit; a pressure control unit for separately controlling the pressure of the transport gas flowing from the pressurization unit to the first solution storage unit and the second solution storage unit; a scaffold injector unit which receives the polymer support structure solution and the emulsifier solution provided by means of the transport gas, and generates and discharges a scaffold dispersion by combining the polymer support structure solution and the emulsifier solution; and a scaffold generation unit which receives the scaffold dispersion discharged through the scaffold injector unit, removes an organic solvent and a dispersion medium contained in the scaffold dispersion, and then generates polymer micro-scaffolds.
Inventors:
CHANG YEONG JUN (KR)
LEE SEUL KI (KR)
CHO BO BAE (KR)
PARK JIN HWAN (KR)
KIM SEOK JAE (KR)
CHOI EUN PYO (KR)
PARK JONG OH (KR)
LEE SEUL KI (KR)
CHO BO BAE (KR)
PARK JIN HWAN (KR)
KIM SEOK JAE (KR)
CHOI EUN PYO (KR)
PARK JONG OH (KR)
Application Number:
PCT/KR2019/016366
Publication Date:
April 01, 2021
Filing Date:
November 26, 2019
Export Citation:
Assignee:
BIOT KOREA INC (KR)
UNIV NAT CHONNAM IND FOUND (KR)
UNIV NAT CHONNAM IND FOUND (KR)
International Classes:
A61L27/56; A61L27/26; A61L27/38
Foreign References:
| KR20110071985A | 2011-06-29 | |||
| KR100924236B1 | 2009-10-29 | |||
| KR101521552B1 | 2015-05-19 | |||
| KR20160039006A | 2016-04-08 | |||
| KR20150097087A | 2015-08-26 |
Other References:
AMOY AV, B. ET AL.: "Microfluidic based fabrication and characterization of highly porous polymeric microspheres", POLYMERS, vol. 11, no. 419, March 2019 (2019-03-01), XP055811381, DOI: 10.3390/polyml 1030419
CHOI, S.-W. ET AL.: "Uniform beads with controllable pore sizes for biomedical applications", SMALL, vol. 6, 2010, pages 1492 - 1498, XP055790525, DOI: 10.1002/smll.201000544
CHOI, S.-W. ET AL.: "Uniform beads with controllable pore sizes for biomedical applications", SMALL, vol. 6, 2010, pages 1492 - 1498, XP055790525, DOI: 10.1002/smll.201000544
Attorney, Agent or Firm:
KIM, Jung Su (KR)
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