Title:
MATERIAL FOR BONE REGENERATION HAVING SURFACE INCLUDING HYDROPHILIZED BIODEGRADABLE FIBERS, AND PRODUCTION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2020/091035
Kind Code:
A1
Abstract:
The polymer surface of biodegradable fibers included in materials for bone regeneration has water repellency and hydrophobicity, and therefore, when such a material is implanted into an affected area, the material repels blood at a very early stage of being mixed with blood, and therefore it takes a long time for the material to be incorporated during an operation. This material for bone regeneration has a surface including hydrophilized biodegradable fibers, wherein the biodegradable fibers included in the material for bone regeneration contain osteogenic particles, and the surfaces of the biodegradable fibers are each substantially entirely covered by an amorphous calcium phosphate layer, and a portion of the calcium phosphate of the amorphous calcium phosphate layer includes carbonate apatite in which the crystal structure of calcium phosphate is replaced with calcium carbonate.
Inventors:
KASUGA TOSHIHIRO (JP)
MATSUBARA TAKASHI (JP)
WATABE MASAO (JP)
OSAKA NAOYA (JP)
MATSUBARA TAKASHI (JP)
WATABE MASAO (JP)
OSAKA NAOYA (JP)
Application Number:
PCT/JP2019/043010
Publication Date:
May 07, 2020
Filing Date:
November 01, 2019
Export Citation:
Assignee:
NAGOYA INST TECH (JP)
ORTHOREBIRTH CO LTD (JP)
ORTHOREBIRTH CO LTD (JP)
International Classes:
A61L27/12; A61L27/14; A61L27/18; A61L27/32; A61L27/40; A61L27/58; D06M11/71; D06M101/32
Domestic Patent References:
| WO2017188435A1 | 2017-11-02 |
Foreign References:
| JPH06285151A | 1994-10-11 | |||
| JP2019183322A | 2019-10-24 |
Other References:
MUCALO, M.R. ET AL.: "Growth of calcium phosphate on surface-modified cotton", JOURNAL OF MATERIALS SCIENCE :MATERIALS IN MEDICINE, vol. 6, 1995, pages 597 - 605, XP55703978
Attorney, Agent or Firm:
NINOMIYA Katsuyuki (JP)
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