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Title:
MEDICINAL COMPOSITION IMPROVING LEPTIN RESISTANCE
Document Type and Number:
WIPO Patent Application WO/2015/033981
Kind Code:
A1
Abstract:
Provided are: a compound represented by formula (I) that improves leptin resistance; a medicinal composition that comprises the compound; a method for manufacturing a medicine for improving leptin resistance, said method comprising using the aforesaid compound; use of the aforesaid compound in manufacturing a medicine for improving leptin resistance; and a method for improving leptin resistance, said method comprising administering the aforesaid compound or medicinal composition. By improving leptin resistance, diseases related to leptin resistance can be treated and/or prevented. The diseases related to leptin resistance that can be treated according to the present invention include, in particular, metabolic disorder, obesity, hyperphagia, fatty liver, diabetes or dyslipidemia.

Inventors:
KAKIZUKA AKIRA (JP)
EBIHARA KEN (JP)
ABE MEGUMI (JP)
EBIHARA CHIHIRO (JP)
Application Number:
PCT/JP2014/073256
Publication Date:
March 12, 2015
Filing Date:
September 03, 2014
Export Citation:
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Assignee:
UNIV KYOTO (JP)
International Classes:
A61K31/4436; A61K31/4418; A61K45/00; A61P1/16; A61P3/00; A61P3/04; A61P3/06; A61P3/10; A61P43/00; C07D213/76; C07D409/04
Domestic Patent References:
WO2012014994A12012-02-02
WO2012043891A12012-04-05
WO2014129495A12014-08-28
WO2012014994A12012-02-02
WO2012043891A12012-04-05
WO1997026265A11997-07-24
WO1999003861A11999-01-28
Foreign References:
US5607915A1997-03-04
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Attorney, Agent or Firm:
SAMEJIMA, Mutsumi et al. (JP)
Mutsumi Sameshima (JP)
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